Explore
Validate
Learn
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [92]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 23673-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- UCP1 antibody
- Antibody type
- Polyclonal
- Description
- UCP1 antibody (Cat. #23673-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Xiasangju alleviate metabolic syndrome by enhancing noradrenaline biosynthesis and activating brown adipose tissue.
Exercise attenuates high-fat diet-induced PVAT dysfunction through improved inflammatory response and BMP4-regulated adipose tissue browning.
Sexual dimorphism in thermogenic regulators and metrnl expression in adipose tissue of offspring mice exposed to maternal and postnatal overnutrition.
Exercise-inducible circulating extracellular vesicle irisin promotes browning and the thermogenic program in white adipose tissue.
Loss of FoxO1 activates an alternate mechanism of mitochondrial quality control for healthy adipose browning.
Global gene expression profiling of perirenal brown adipose tissue whitening in goat kids reveals novel genes linked to adipose remodeling.
Eugenol mimics exercise to promote skeletal muscle fiber remodeling and myokine IL-15 expression by activating TRPV1 channel.
Structural Variances in Curcumin Degradants: Impact on Obesity in Mice.
MIIP downregulation drives colorectal cancer progression through inducing peri-cancerous adipose tissue browning.
Dysregulation of mitochondrial dynamics mediated aortic perivascular adipose tissue-associated vascular reactivity impairment under excessive fructose intake.
Brown adipose Vanin-1 is required for the maintenance of mitochondrial homeostasis and prevents diet-induced metabolic dysfunction.
miR-1182-mediated ALDH3A2 inhibition affects lipid metabolism and progression in ccRCC by activating the PI3K-AKT pathway.
Whitening of brown adipose tissue inhibits osteogenic differentiation via secretion of S100A8/A9.
Repurposing lansoprazole to alleviate metabolic syndrome via PHOSPHO1 inhibition.
Pterostilbene Enhances Thermogenesis and Mitochondrial Biogenesis by Activating the SIRT1/PGC-1α/SIRT3 Pathway to Prevent Western Diet-Induced Obesity.
Polysaccharide from Ziyang Selenium-Enriched Green Tea Prevents Obesity and Promotes Adipose Thermogenesis via Modulating the Gut Microbiota.
Acetyl-coenzyme A acetyltransferase 1 promotes brown adipogenesis by activating the AMPK-PGC1α signaling pathway.
Geniposide ameliorates atherosclerosis by regulating macrophage polarization via perivascular adipocyte-derived CXCL14.
Miquelianin in Folium Nelumbinis extract promotes white-to-beige fat conversion via blocking AMPK/DRP1/mitophagy and modulating gut microbiota in HFD-fed mice.
HDAC1 inhibits beige adipocyte-mediated thermogenesis through histone crotonylation of Pgc1a/Ucp1.
CX3CR1(hi) macrophages sustain metabolic adaptation by relieving adipose-derived stem cell senescence in visceral adipose tissue.
Metrnl Alleviates Lipid Accumulation by Modulating Mitochondrial Homeostasis in Diabetic Nephropathy.
Bioactivity-based molecular networking-guided identification of guttiferone J from Garcinia cambogia as an anti-obesity candidate.
Adipocyte YTH N(6)-methyladenosine RNA-binding protein 1 protects against obesity by promoting white adipose tissue beiging in male mice.
FoxO1 regulates adipose transdifferentiation and iron influx by mediating Tgfβ1 signaling pathway.
Hypoxia promotes white adipose tissues browning in rats under simulated environment at altitude of 5000 m.
T-cell immunoglobulin- and mucin-domain-containing molecule-4 maintains adipose tissue homeostasis by orchestrating M2 macrophage polarization via nuclear factor kappa B pathway.
Knockout of ICAT in Adipose Tissue Alleviates Fibro-inflammation in Obese Mice.
Increased BAT Thermogenesis in Male Mouse Apolipoprotein A4 Transgenic Mice.
Lipopolysaccharide-induced persistent inflammation ameliorates fat accumulation by promoting adipose browning in vitro and in vivo.
CCE and EODF as two distinct non-shivering thermogenesis models inducing weight loss.
Muscle-specific ER-associated degradation maintains postnatal muscle hypertrophy and systemic energy metabolism.
Interference of a mammalian circRNA regulates lipid metabolism reprogramming by targeting miR-24-3p/Igf2/PI3K-AKT-mTOR and Igf2bp2/Ucp1 axis.
Transcriptome-based selection and validation of optimal reference genes in perirenal adipose developing of goat (Capra hircus).
Comprehensive Analysis and Validation of Solute Carrier Family 25 (SLC25) and Its Correlation with Immune Infiltration in Pan-Cancer.
Ceiling culture of human mature white adipocytes with a browning agent: A novel approach to induce transdifferentiation into beige adipocytes.
Naringenin activates beige adipocyte browning in high fat diet-fed C57BL/6 mice by shaping the gut microbiota.
Artemisia sphaerocephala Krasch polysaccharide promotes adipose thermogenesis and decreases obesity by shaping the gut microbiota.
Irisin reduces the abnormal reproductive and metabolic phenotypes of PCOS by regulating the activity of brown adipose tissue in mice†.
A tumor-suppressive function for Notch3 in the parous mammary gland.
Dysregulated adipose tissue expansion and impaired adipogenesis in Prader-Willi syndrome children before obesity-onset.
Functional Attenuation of UCP1 as the Potential Mechanism for a Thickened Blubber Layer in Cetaceans.
Adenosine-rich extract of Ganoderma lucidum: A safe and effective lipid-lowering substance.
Pu-erh tea increases the metabolite Cinnabarinic acid to improve circadian rhythm disorder-induced obesity.
Lytic cocktail: An effective method to alleviate severe burn induced hyper-metabolism through regulating white adipose tissue browning.
Effects of maternal feed intake restriction on the blood parameters, fatty acid profile and lipogenetic genes expression of perirenal fat in offspring kids.
Knockdown of VEGFB/VEGFR1 Signaling Promotes White Adipose Tissue Browning and Skeletal Muscle Development.
Parathyroid hormone-related protein prevents high-fat-diet-induced obesity, hepatic steatosis and insulin resistance in mice.
Dopamine receptor D1 signaling stimulates lipolysis and browning of white adipocytes.
Inhibition of high-fat diet-induced obesity via reduction of ER-resident protein Nogo occurs through multiple mechanisms.
Dietary succinate supplementation to maternal mice improves fetal brown adipose tissue development and thermogenesis of female offspring.
Quercetin, Engelitin and Caffeic Acid of Smilax china L. Polyphenols, Stimulate 3T3-L1 Adipocytes to Brown-like Adipocytes Via β3-AR/AMPK Signaling Pathway.
miR-669a-5p promotes adipogenic differentiation and induces browning in preadipocytes.
Cold exposure prevents fat accumulation in striped hamsters refed a high-fat diet following food restriction.
Gold nanoclusters eliminate obesity induced by antipsychotics.
Transcription Factor E2F1 Knockout Promotes Mice White Adipose Tissue Browning Through Autophagy Inhibition.
Empagliflozin Induces White Adipocyte Browning and Modulates Mitochondrial Dynamics in KK Cg-Ay/J Mice and Mouse Adipocytes.
DMRT2 Interacts With FXR and Improves Insulin Resistance in Adipocytes and a Mouse Model.
Vitellogenin 2 promotes muscle development and stimulates the browning of white fat.
Vitamin D/VDR regulates peripheral energy homeostasis via central renin-angiotensin system.
Exposure to melamine cyanuric acid in adult mice induced thyroid dysfunction and circadian rhythm disorder.
Aqueous extracts of Aconite promote thermogenesis in rats with hypothermia via regulating gut microbiota and bile acid metabolism.
Curcumin improves adipocytes browning and mitochondrial function in 3T3-L1 cells and obese rodent model.
A flavonoid-rich Smilax china L. extract prevents obesity by upregulating the adiponectin-receptor/AMPK signalling pathway and modulating the gut microbiota in mice.
Improvement of obesity-associated disorders by a small-molecule drug targeting mitochondria of adipose tissue macrophages.
Skip participates in formation and lipid metabolism of beige adipose and might mediate the effects of SIRT1 activator BTM-0512 on beige remodeling.
Nobiletin activates thermogenesis of brown and white adipose tissue in high-fat diet-fed C57BL/6 mice by shaping the gut microbiota.
Gentisic acid prevents diet-induced obesity in mice by accelerating the thermogenesis of brown adipose tissue.
Cbl Proto-Oncogene B (CBLB) c.197A>T Mutation Induces Mild Metabolic Dysfunction in Partial Type I Multiple Symmetric Lipomatosis (MSL).
Anti-Adipogenic Effect of Theabrownin Is Mediated by Bile Acid Alternative Synthesis via Gut Microbiota Remodeling.
A dysregulated bile acid-gut microbiota axis contributes to obesity susceptibility.
Supplementation with Extracellular Vesicles Derived from Adipose-Derived Stem Cells Increases Fat Graft Survival and Browning in Mice: A Cell-Free Approach to Construct Beige Fat from White Fat Grafting.
ChREBP-β regulates thermogenesis in brown adipose tissue.
TSH promotes adiposity by inhibiting the browning of white fat.
Feeding induces cholesterol biosynthesis via the mTORC1-USP20-HMGCR axis.
p66Shc Contributes to Liver Fibrosis through the Regulation of Mitochondrial Reactive Oxygen Species.
Lipid Profiling Reveals Browning Heterogeneity of White Adipose Tissue by Β3-Adrenergic Stimulation.
Metabolic and endocrinal effects of N-desmethyl-olanzapine in mice with obesity: Implication for olanzapine-associated metabolic changes.
Gpnmb secreted from liver promotes lipogenesis in white adipose tissue and aggravates obesity and insulin resistance.
Deficiency of heat shock protein A12A promotes browning of white adipose tissues in mice.
Gdf11 gene transfer prevents high fat diet-induced obesity and improves metabolic homeostasis in obese and STZ-induced diabetic mice.
Identification of a natural beige adipose depot in mice.
Zinc-α2-Glycoprotein Is Associated with Obesity in Chinese People and HFD-Induced Obese Mice.
The Protective Effects of Danggui-Baizhu-Tang on High-Fat Diet-Induced Obesity in Mice by Activating Thermogenesis.
Renoprotective Effect of Danhong Injection on Streptozotocin-Induced Diabetic Rats through a Peroxisome Proliferator-Activated Receptor γ Mediated Pathway.
Exosomes From Adipose-Derived Stem Cells Attenuate Adipose Inflammation and Obesity Through Polarizing M2 Macrophages and Beiging in White Adipose Tissue.
Antiobesity effect of Lactobacillus reuteri 263 associated with energy metabolism remodeling of white adipose tissue in high-energy-diet-fed rats.
Green tea extract induces genes related to browning of white adipose tissue and limits weight-gain in high energy diet-fed rat.
Pdcd4 restrains the self-renewal and white-to-beige transdifferentiation of adipose-derived stem cells.
Liraglutide suppresses obesity and induces brown fat-like phenotype via Soluble Guanylyl Cyclase mediated pathway in vivo and in vitro.
Programmed cell death-4 deficiency prevents diet-induced obesity, adipose tissue inflammation, and insulin resistance.
Zinc-alpha2-glycoprotein is involved in regulation of body weight through inhibition of lipogenic enzymes in adipose tissue.
He C, An Y, Shi L, Huang Y, Zhang H, Fu W, Wang M, Shan Z, Du Y, Xie J, Huang Z, Sun W, Zhao Y, Zhao B
Frontiers in pharmacology 2024;15:1371929
Frontiers in pharmacology 2024;15:1371929
Exercise attenuates high-fat diet-induced PVAT dysfunction through improved inflammatory response and BMP4-regulated adipose tissue browning.
Liu X, Jiang X, Hu J, Ding M, Lee SK, Korivi M, Qian Y, Li T, Wang L, Li W
Frontiers in nutrition 2024;11:1393343
Frontiers in nutrition 2024;11:1393343
Sexual dimorphism in thermogenic regulators and metrnl expression in adipose tissue of offspring mice exposed to maternal and postnatal overnutrition.
Yang Z, Jiang J, Tan Y, Yang G, Chen M, Huang J, Liu J, Wei X, Wang S, Luo X, Han Z
Journal of physiology and biochemistry 2024 May;80(2):407-420
Journal of physiology and biochemistry 2024 May;80(2):407-420
Exercise-inducible circulating extracellular vesicle irisin promotes browning and the thermogenic program in white adipose tissue.
Shi H, Hao X, Sun Y, Zhao Y, Wang Y, Cao X, Gong Z, Ji S, Lu J, Yan Y, Yu X, Luo X, Wang J, Wang H
Acta physiologica (Oxford, England) 2024 Mar;240(3):e14103
Acta physiologica (Oxford, England) 2024 Mar;240(3):e14103
Loss of FoxO1 activates an alternate mechanism of mitochondrial quality control for healthy adipose browning.
Shi L, Yang J, Tao Z, Zheng L, Bui TF, Alonso RL, Yue F, Cheng Z
Clinical science (London, England : 1979) 2024 Mar 20;138(6):371-385
Clinical science (London, England : 1979) 2024 Mar 20;138(6):371-385
Global gene expression profiling of perirenal brown adipose tissue whitening in goat kids reveals novel genes linked to adipose remodeling.
Zhao L, Yang H, Li M, Xiao M, Li X, Cheng L, Cheng W, Chen M, Zhao Y
Journal of animal science and biotechnology 2024 Mar 14;15(1):47
Journal of animal science and biotechnology 2024 Mar 14;15(1):47
Eugenol mimics exercise to promote skeletal muscle fiber remodeling and myokine IL-15 expression by activating TRPV1 channel.
Huang T, Chen X, He J, Zheng P, Luo Y, Wu A, Yan H, Yu B, Chen D, Huang Z
eLife 2024 Jun 24;12
eLife 2024 Jun 24;12
Structural Variances in Curcumin Degradants: Impact on Obesity in Mice.
Koh YC, Hsu HW, Ho PY, Hsu KY, Lin WS, Nagabhushanam K, Ho CT, Pan MH
Journal of agricultural and food chemistry 2024 Jul 3;72(26):14786-14798
Journal of agricultural and food chemistry 2024 Jul 3;72(26):14786-14798
MIIP downregulation drives colorectal cancer progression through inducing peri-cancerous adipose tissue browning.
Wang Q, Su Y, Sun R, Xiong X, Guo K, Wei M, Yang G, Ru Y, Zhang Z, Li J, Zhang J, Qiao Q, Li X
Cell & bioscience 2024 Jan 20;14(1):12
Cell & bioscience 2024 Jan 20;14(1):12
Dysregulation of mitochondrial dynamics mediated aortic perivascular adipose tissue-associated vascular reactivity impairment under excessive fructose intake.
Wu KLH, Wu CW, Chen LW, Chang HH, Cheng CL, Wu CY, Lee YC, Chen IC, Hung CY, Liu WC
Nutrition & metabolism 2024 Jan 2;21(1):4
Nutrition & metabolism 2024 Jan 2;21(1):4
Brown adipose Vanin-1 is required for the maintenance of mitochondrial homeostasis and prevents diet-induced metabolic dysfunction.
Sun C, Liang J, Zheng J, Mao S, Chen S, Aikemu A, Liu C
Molecular metabolism 2024 Feb;80:101884
Molecular metabolism 2024 Feb;80:101884
miR-1182-mediated ALDH3A2 inhibition affects lipid metabolism and progression in ccRCC by activating the PI3K-AKT pathway.
Lv Q, Shi J, Miao D, Tan D, Zhao C, Xiong Z, Zhang X
Translational oncology 2024 Feb;40:101835
Translational oncology 2024 Feb;40:101835
Whitening of brown adipose tissue inhibits osteogenic differentiation via secretion of S100A8/A9.
Wang T, Zhao C, Zhang J, Li S, Zhang Y, Gong Y, Zhou Y, Yan L, Zhang S, Zhang Z, Hu H, Liu A, Bai X, Zou Z
iScience 2024 Feb 16;27(2):108857
iScience 2024 Feb 16;27(2):108857
Repurposing lansoprazole to alleviate metabolic syndrome via PHOSPHO1 inhibition.
Wu Y, Xin J, Li X, Yang T, Liu Y, Zhao Y, Xie W, Jiang M
Acta pharmaceutica Sinica. B 2024 Apr;14(4):1711-1725
Acta pharmaceutica Sinica. B 2024 Apr;14(4):1711-1725
Pterostilbene Enhances Thermogenesis and Mitochondrial Biogenesis by Activating the SIRT1/PGC-1α/SIRT3 Pathway to Prevent Western Diet-Induced Obesity.
Koh YC, Lin SJ, Hsu KY, Nagabhushanam K, Ho CT, Pan MH
Molecular nutrition & food research 2023 Sep;67(18):e2300370
Molecular nutrition & food research 2023 Sep;67(18):e2300370
Polysaccharide from Ziyang Selenium-Enriched Green Tea Prevents Obesity and Promotes Adipose Thermogenesis via Modulating the Gut Microbiota.
Li D, Cheng Y, Zeng X, Li Y, Xia Z, Yang X, Ren D
Journal of agricultural and food chemistry 2023 Sep 13;71(36):13363-13375
Journal of agricultural and food chemistry 2023 Sep 13;71(36):13363-13375
Acetyl-coenzyme A acetyltransferase 1 promotes brown adipogenesis by activating the AMPK-PGC1α signaling pathway.
Zhu K, Ni L, Han J, Yan Z, Zhang Y, Wang F, Wang L, Yang X
Biochimica et biophysica acta. Molecular and cell biology of lipids 2023 Oct;1868(10):159369
Biochimica et biophysica acta. Molecular and cell biology of lipids 2023 Oct;1868(10):159369
Geniposide ameliorates atherosclerosis by regulating macrophage polarization via perivascular adipocyte-derived CXCL14.
He P, Wang H, Cheng S, Hu F, Zhang L, Chen W, Xu Y, Zhang Y, Gu Y, Li Z, Jin Y, Liu X, Jia Y
Journal of ethnopharmacology 2023 Oct 5;314:116532
Journal of ethnopharmacology 2023 Oct 5;314:116532
Miquelianin in Folium Nelumbinis extract promotes white-to-beige fat conversion via blocking AMPK/DRP1/mitophagy and modulating gut microbiota in HFD-fed mice.
Wang Z, Yang T, Zeng M, Wang Z, Chen Q, Chen J, Christian M, He Z
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Nov;181:114089
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Nov;181:114089
HDAC1 inhibits beige adipocyte-mediated thermogenesis through histone crotonylation of Pgc1a/Ucp1.
Tian D, Zeng X, Gong Y, Zheng Y, Zhang J, Wu Z
Cellular signalling 2023 Nov;111:110875
Cellular signalling 2023 Nov;111:110875
CX3CR1(hi) macrophages sustain metabolic adaptation by relieving adipose-derived stem cell senescence in visceral adipose tissue.
Zhou Z, Zhang H, Tao Y, Jie H, Zhao J, Zang J, Li H, Wang Y, Wang T, Zhao H, Li Y, Guo C, Zhu F, Mao H, Zhang L, Liu F, Wang Q
Cell reports 2023 May 30;42(5):112424
Cell reports 2023 May 30;42(5):112424
Metrnl Alleviates Lipid Accumulation by Modulating Mitochondrial Homeostasis in Diabetic Nephropathy.
Zhou Y, Liu L, Jin B, Wu Y, Xu L, Chang X, Hu L, Wang G, Huang Y, Song L, Zhang T, Wang Y, Xiao Y, Zhang F, Shi M, Liu L, Wang T, Yan R, Guo B
Diabetes 2023 May 1;72(5):611-626
Diabetes 2023 May 1;72(5):611-626
Bioactivity-based molecular networking-guided identification of guttiferone J from Garcinia cambogia as an anti-obesity candidate.
Feng Z, Chen J, Chen C, Feng L, Wang R, Zhu J, Lou R, Liu J, Ye Y, Lin L
British journal of pharmacology 2023 Mar;180(5):589-608
British journal of pharmacology 2023 Mar;180(5):589-608
Adipocyte YTH N(6)-methyladenosine RNA-binding protein 1 protects against obesity by promoting white adipose tissue beiging in male mice.
Yan S, Zhou X, Wu C, Gao Y, Qian Y, Hou J, Xie R, Han B, Chen Z, Wei S, Gao X
Nature communications 2023 Mar 13;14(1):1379
Nature communications 2023 Mar 13;14(1):1379
FoxO1 regulates adipose transdifferentiation and iron influx by mediating Tgfβ1 signaling pathway.
Shi L, Tao Z, Zheng L, Yang J, Hu X, Scott K, de Kloet A, Krause E, Collins JF, Cheng Z
Redox biology 2023 Jul;63:102727
Redox biology 2023 Jul;63:102727
Hypoxia promotes white adipose tissues browning in rats under simulated environment at altitude of 5000 m.
Song Q, Liu S, Wang J, Chai J, Wen J, Xu C
Biochemical and biophysical research communications 2023 Jul 23;666:146-153
Biochemical and biophysical research communications 2023 Jul 23;666:146-153
T-cell immunoglobulin- and mucin-domain-containing molecule-4 maintains adipose tissue homeostasis by orchestrating M2 macrophage polarization via nuclear factor kappa B pathway.
Ding L, Liang Y, Wang Y, Tong Z, Liu W, Tan S, Zhang J, Wang Y, Wu Z, Liang X, Ma C, Gao L
Immunology 2023 Jan;168(1):49-62
Immunology 2023 Jan;168(1):49-62
Knockout of ICAT in Adipose Tissue Alleviates Fibro-inflammation in Obese Mice.
Song Z, Liu N, He Y, Chen J, Li J, Wang F, Wu Z
Inflammation 2023 Feb;46(1):404-417
Inflammation 2023 Feb;46(1):404-417
Increased BAT Thermogenesis in Male Mouse Apolipoprotein A4 Transgenic Mice.
LaRussa Z, Kuo HN, West K, Shen Z, Wisniewski K, Tso P, Coschigano KT, Lo CC
International journal of molecular sciences 2023 Feb 20;24(4)
International journal of molecular sciences 2023 Feb 20;24(4)
Lipopolysaccharide-induced persistent inflammation ameliorates fat accumulation by promoting adipose browning in vitro and in vivo.
Zhang W, Liu S, Kong L, Wu S, Zhong Z, Yu L, Yang Q, Zhang J, Li J, Zheng G
International journal of biological macromolecules 2023 Dec 1;252:126511
International journal of biological macromolecules 2023 Dec 1;252:126511
CCE and EODF as two distinct non-shivering thermogenesis models inducing weight loss.
Xu T, Wang J, Shi H, Wei X, Zhang H, Ji Y, Lu S, Yan Y, Yu X, Luo X, Wang H
Pflugers Archiv : European journal of physiology 2023 Aug;475(8):961-974
Pflugers Archiv : European journal of physiology 2023 Aug;475(8):961-974
Muscle-specific ER-associated degradation maintains postnatal muscle hypertrophy and systemic energy metabolism.
Abdon B, Liang Y, da Luz Scheffer D, Torres M, Shrestha N, Reinert RB, Lu Y, Pederson B, Bugarin-Lapuz A, Kersten S, Qi L
JCI insight 2023 Aug 3;8(17)
JCI insight 2023 Aug 3;8(17)
Interference of a mammalian circRNA regulates lipid metabolism reprogramming by targeting miR-24-3p/Igf2/PI3K-AKT-mTOR and Igf2bp2/Ucp1 axis.
Shao J, Wang M, Zhang A, Liu Z, Jiang G, Tang T, Wang J, Jia X, Lai S
Cellular and molecular life sciences : CMLS 2023 Aug 17;80(9):252
Cellular and molecular life sciences : CMLS 2023 Aug 17;80(9):252
Transcriptome-based selection and validation of optimal reference genes in perirenal adipose developing of goat (Capra hircus).
Zhao L, Yang H, Li X, Zhou Y, Liu T, Zhao Y
Frontiers in veterinary science 2022;9:1055866
Frontiers in veterinary science 2022;9:1055866
Comprehensive Analysis and Validation of Solute Carrier Family 25 (SLC25) and Its Correlation with Immune Infiltration in Pan-Cancer.
Liu AR, Liu YN, Shen SX, Yan LR, Lv Z, Ding HX, Wang A, Yuan Y, Xu Q
BioMed research international 2022;2022:4009354
BioMed research international 2022;2022:4009354
Ceiling culture of human mature white adipocytes with a browning agent: A novel approach to induce transdifferentiation into beige adipocytes.
He Y, Liang Z, Wang J, Tang H, Li J, Cai J, Liao Y
Frontiers in bioengineering and biotechnology 2022;10:905194
Frontiers in bioengineering and biotechnology 2022;10:905194
Naringenin activates beige adipocyte browning in high fat diet-fed C57BL/6 mice by shaping the gut microbiota.
Zhang S, Li J, Shi X, Tan X, Si Q
Food & function 2022 Oct 3;13(19):9918-9930
Food & function 2022 Oct 3;13(19):9918-9930
Artemisia sphaerocephala Krasch polysaccharide promotes adipose thermogenesis and decreases obesity by shaping the gut microbiota.
Zeng X, Ren D, Li D, Du H, Yang X
Food & function 2022 Oct 17;13(20):10651-10664
Food & function 2022 Oct 17;13(20):10651-10664
Irisin reduces the abnormal reproductive and metabolic phenotypes of PCOS by regulating the activity of brown adipose tissue in mice†.
Zheng Y, He J, Yang D, Yuan M, Liu S, Dai F, Jia Y, Cheng Y
Biology of reproduction 2022 Oct 11;107(4):1046-1058
Biology of reproduction 2022 Oct 11;107(4):1046-1058
A tumor-suppressive function for Notch3 in the parous mammary gland.
Chung WC, Egan SE, Xu K
Development (Cambridge, England) 2022 Oct 1;149(19)
Development (Cambridge, England) 2022 Oct 1;149(19)
Dysregulated adipose tissue expansion and impaired adipogenesis in Prader-Willi syndrome children before obesity-onset.
Chao Y, Gao L, Wang X, Cai Y, Shu Y, Zou X, Qin Y, Hu C, Dai Y, Zhu M, Shen Z, Zou C
Metabolism: clinical and experimental 2022 Nov;136:155295
Metabolism: clinical and experimental 2022 Nov;136:155295
Functional Attenuation of UCP1 as the Potential Mechanism for a Thickened Blubber Layer in Cetaceans.
Zhou M, Wu T, Chen Y, Xu S, Yang G
Molecular biology and evolution 2022 Nov 3;39(11)
Molecular biology and evolution 2022 Nov 3;39(11)
Adenosine-rich extract of Ganoderma lucidum: A safe and effective lipid-lowering substance.
Li H, Du Y, Ji H, Yang Y, Xu C, Li Q, Ran L, Wu C, Zhou Q, Wu S
iScience 2022 Nov 18;25(11):105214
iScience 2022 Nov 18;25(11):105214
Pu-erh tea increases the metabolite Cinnabarinic acid to improve circadian rhythm disorder-induced obesity.
Hu S, Hu C, Luo L, Zhang H, Zhao S, Liu Z, Zeng L
Food chemistry 2022 Nov 15;394:133500
Food chemistry 2022 Nov 15;394:133500
Lytic cocktail: An effective method to alleviate severe burn induced hyper-metabolism through regulating white adipose tissue browning.
Zhang M, Yang P, Yu T, Harmsen MC, Gao M, Liu D, Shi Y, Liu Y, Zhang X
Heliyon 2022 Mar;8(3):e09128
Heliyon 2022 Mar;8(3):e09128
Effects of maternal feed intake restriction on the blood parameters, fatty acid profile and lipogenetic genes expression of perirenal fat in offspring kids.
Chen W, Yang H, Yan Q, Zhou X, Tan Z, Wang Z
Animal reproduction science 2022 Mar;238:106955
Animal reproduction science 2022 Mar;238:106955
Knockdown of VEGFB/VEGFR1 Signaling Promotes White Adipose Tissue Browning and Skeletal Muscle Development.
Ling M, Lai X, Quan L, Li F, Lang L, Fu Y, Feng S, Yi X, Zhu C, Gao P, Zhu X, Wang L, Shu G, Jiang Q, Wang S
International journal of molecular sciences 2022 Jul 7;23(14)
International journal of molecular sciences 2022 Jul 7;23(14)
Parathyroid hormone-related protein prevents high-fat-diet-induced obesity, hepatic steatosis and insulin resistance in mice.
Qin B, Qincao L, He S, Liao Y, Shi J, Xie F, Diao N, Bai L
Endocrine journal 2022 Jan 28;69(1):55-65
Endocrine journal 2022 Jan 28;69(1):55-65
Dopamine receptor D1 signaling stimulates lipolysis and browning of white adipocytes.
Yu J, Zhu J, Deng J, Shen J, Du F, Wu X, Chen Y, Li M, Wen Q, Xiao Z, Zhao Y
Biochemical and biophysical research communications 2022 Jan 15;588:83-89
Biochemical and biophysical research communications 2022 Jan 15;588:83-89
Inhibition of high-fat diet-induced obesity via reduction of ER-resident protein Nogo occurs through multiple mechanisms.
Wang X, Yang Y, Zhao D, Zhang S, Chen Y, Chen Y, Feng K, Li X, Han J, Iwakiri Y, Duan Y, Yang X
The Journal of biological chemistry 2022 Feb;298(2):101561
The Journal of biological chemistry 2022 Feb;298(2):101561
Dietary succinate supplementation to maternal mice improves fetal brown adipose tissue development and thermogenesis of female offspring.
Liu X, Chen Y, Zhao L, Tian Q, deAvila JM, Zhu MJ, Du M
The Journal of nutritional biochemistry 2022 Feb;100:108908
The Journal of nutritional biochemistry 2022 Feb;100:108908
Quercetin, Engelitin and Caffeic Acid of Smilax china L. Polyphenols, Stimulate 3T3-L1 Adipocytes to Brown-like Adipocytes Via β3-AR/AMPK Signaling Pathway.
Kong L, Zhang W, Liu S, Zhong Z, Zheng G
Plant foods for human nutrition (Dordrecht, Netherlands) 2022 Dec;77(4):529-537
Plant foods for human nutrition (Dordrecht, Netherlands) 2022 Dec;77(4):529-537
miR-669a-5p promotes adipogenic differentiation and induces browning in preadipocytes.
Tan X, Zhu T, Zhang L, Fu L, Hu Y, Li H, Li C, Zhang J, Liang B, Liu J
Adipocyte 2022 Dec;11(1):120-132
Adipocyte 2022 Dec;11(1):120-132
Cold exposure prevents fat accumulation in striped hamsters refed a high-fat diet following food restriction.
Huo DL, Bao MH, Cao J, Zhao ZJ
BMC zoology 2022 Apr 18;7(1):19
BMC zoology 2022 Apr 18;7(1):19
Gold nanoclusters eliminate obesity induced by antipsychotics.
He M, Yao J, Zhang Z, Zhang Y, Chen R, Gu Z, Huang X, Deng C, Zhou R, Fan J, Zhang B, Xie Y, Gao G, Sun T
Scientific reports 2022 Apr 1;12(1):5502
Scientific reports 2022 Apr 1;12(1):5502
Transcription Factor E2F1 Knockout Promotes Mice White Adipose Tissue Browning Through Autophagy Inhibition.
Xiong M, Hu W, Tan Y, Yu H, Zhang Q, Zhao C, Yi Y, Wang Y, Wu Y, Wu M
Frontiers in physiology 2021;12:748040
Frontiers in physiology 2021;12:748040
Empagliflozin Induces White Adipocyte Browning and Modulates Mitochondrial Dynamics in KK Cg-Ay/J Mice and Mouse Adipocytes.
Xu L, Xu C, Liu X, Li X, Li T, Yu X, Xue M, Yang J, Kosmas CE, Moris D, Sanchis-Gomar F, Yoshida N, Berger NA, Aronow WS, Sun B, Chen L
Frontiers in physiology 2021;12:745058
Frontiers in physiology 2021;12:745058
DMRT2 Interacts With FXR and Improves Insulin Resistance in Adipocytes and a Mouse Model.
Tao J, Yu XL, Yuan YJ, Shen X, Liu J, Gu PP, Wang Z, Ma YT, Li GQ
Frontiers in endocrinology 2021;12:723623
Frontiers in endocrinology 2021;12:723623
Vitellogenin 2 promotes muscle development and stimulates the browning of white fat.
Li Y, Sun X, Bai Y, Ji Y, Ren H, Yu X, Yan Y, He X, Dong Y, Zhang L, Luo X, Wang H
Aging 2021 Oct 5;13(19):22985-23003
Aging 2021 Oct 5;13(19):22985-23003
Vitamin D/VDR regulates peripheral energy homeostasis via central renin-angiotensin system.
Su H, Liu N, Zhang Y, Kong J
Journal of advanced research 2021 Nov;33:69-80
Journal of advanced research 2021 Nov;33:69-80
Exposure to melamine cyanuric acid in adult mice induced thyroid dysfunction and circadian rhythm disorder.
Wang S, Wang S, Wang C, Feng D, Feng X
Ecotoxicology and environmental safety 2021 Nov 19;228:112992
Ecotoxicology and environmental safety 2021 Nov 19;228:112992
Aqueous extracts of Aconite promote thermogenesis in rats with hypothermia via regulating gut microbiota and bile acid metabolism.
Liu J, Tan Y, Ao H, Feng W, Peng C
Chinese medicine 2021 Mar 19;16(1):29
Chinese medicine 2021 Mar 19;16(1):29
Curcumin improves adipocytes browning and mitochondrial function in 3T3-L1 cells and obese rodent model.
Zhao D, Pan Y, Yu N, Bai Y, Ma R, Mo F, Zuo J, Chen B, Jia Q, Zhang D, Liu J, Jiang G, Gao S
Royal Society open science 2021 Mar 17;8(3):200974
Royal Society open science 2021 Mar 17;8(3):200974
A flavonoid-rich Smilax china L. extract prevents obesity by upregulating the adiponectin-receptor/AMPK signalling pathway and modulating the gut microbiota in mice.
Li X, Yang L, Li J, Lin L, Zheng G
Food & function 2021 Jul 5;12(13):5862-5875
Food & function 2021 Jul 5;12(13):5862-5875
Improvement of obesity-associated disorders by a small-molecule drug targeting mitochondria of adipose tissue macrophages.
Wang Y, Tang B, Long L, Luo P, Xiang W, Li X, Wang H, Jiang Q, Tan X, Luo S, Li H, Wang Z, Chen Z, Leng Y, Jiang Z, Wang Y, Ma L, Wang R, Zeng C, Liu Z, Wang Y, Miao H, Shi C
Nature communications 2021 Jan 4;12(1):102
Nature communications 2021 Jan 4;12(1):102
Skip participates in formation and lipid metabolism of beige adipose and might mediate the effects of SIRT1 activator BTM-0512 on beige remodeling.
Liao ZM, Li AN, Cai Y, Chen JJ, Xu Y, Sui LH, Wang JL, Jin P, Wang KS, Yang ZC
Biochemical and biophysical research communications 2021 Jan 22;537:109-117
Biochemical and biophysical research communications 2021 Jan 22;537:109-117
Nobiletin activates thermogenesis of brown and white adipose tissue in high-fat diet-fed C57BL/6 mice by shaping the gut microbiota.
Kou G, Li P, Hu Y, Chen H, Nyantakyiwaa Amoah A, Seydou Traore S, Cui Z, Lyu Q
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Feb;35(2):e21267
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Feb;35(2):e21267
Gentisic acid prevents diet-induced obesity in mice by accelerating the thermogenesis of brown adipose tissue.
Han X, Guo J, Gao Y, Zhan J, You Y, Huang W
Food & function 2021 Feb 15;12(3):1262-1270
Food & function 2021 Feb 15;12(3):1262-1270
Cbl Proto-Oncogene B (CBLB) c.197A>T Mutation Induces Mild Metabolic Dysfunction in Partial Type I Multiple Symmetric Lipomatosis (MSL).
Chen K, Wan X, Zhao L, Zhao S, Peng L, Yang W, Yuan J, Zhu L, Mo Z
Diabetes, metabolic syndrome and obesity : targets and therapy 2020;13:3535-3549
Diabetes, metabolic syndrome and obesity : targets and therapy 2020;13:3535-3549
Anti-Adipogenic Effect of Theabrownin Is Mediated by Bile Acid Alternative Synthesis via Gut Microbiota Remodeling.
Kuang J, Zheng X, Huang F, Wang S, Li M, Zhao M, Sang C, Ge K, Li Y, Li J, Rajani C, Ma X, Zhou S, Zhao A, Jia W
Metabolites 2020 Nov 23;10(11)
Metabolites 2020 Nov 23;10(11)
A dysregulated bile acid-gut microbiota axis contributes to obesity susceptibility.
Wei M, Huang F, Zhao L, Zhang Y, Yang W, Wang S, Li M, Han X, Ge K, Qu C, Rajani C, Xie G, Zheng X, Zhao A, Bian Z, Jia W
EBioMedicine 2020 May;55:102766
EBioMedicine 2020 May;55:102766
Supplementation with Extracellular Vesicles Derived from Adipose-Derived Stem Cells Increases Fat Graft Survival and Browning in Mice: A Cell-Free Approach to Construct Beige Fat from White Fat Grafting.
Zhu YZ, Zhang J, Hu X, Wang ZH, Wu S, Yi YY
Plastic and reconstructive surgery 2020 May;145(5):1183-1195
Plastic and reconstructive surgery 2020 May;145(5):1183-1195
ChREBP-β regulates thermogenesis in brown adipose tissue.
Wei C, Ma X, Su K, Qi S, Zhu Y, Lin J, Wang C, Yang R, Chen X, Wang W, Zhang WJ
The Journal of endocrinology 2020 Jun;245(3):343-356
The Journal of endocrinology 2020 Jun;245(3):343-356
TSH promotes adiposity by inhibiting the browning of white fat.
Zhang J, Wu H, Ma S, Gao L, Yu C, Jing F, Zhao J
Adipocyte 2020 Dec;9(1):264-278
Adipocyte 2020 Dec;9(1):264-278
Feeding induces cholesterol biosynthesis via the mTORC1-USP20-HMGCR axis.
Lu XY, Shi XJ, Hu A, Wang JQ, Ding Y, Jiang W, Sun M, Zhao X, Luo J, Qi W, Song BL
Nature 2020 Dec;588(7838):479-484
Nature 2020 Dec;588(7838):479-484
p66Shc Contributes to Liver Fibrosis through the Regulation of Mitochondrial Reactive Oxygen Species.
Zhao Y, Wang Z, Feng D, Zhao H, Lin M, Hu Y, Zhang N, Lv L, Gao Z, Zhai X, Tian X, Yao J
Theranostics 2019;9(5):1510-1522
Theranostics 2019;9(5):1510-1522
Lipid Profiling Reveals Browning Heterogeneity of White Adipose Tissue by Β3-Adrenergic Stimulation.
He P, Hou B, Li Y, Xu C, Ma P, Lam SM, Gil V, Yang X, Yang X, Zhang L, Shui G, Song J, Qiang G, Liew CW, Du G
Biomolecules 2019 Sep 3;9(9)
Biomolecules 2019 Sep 3;9(9)
Metabolic and endocrinal effects of N-desmethyl-olanzapine in mice with obesity: Implication for olanzapine-associated metabolic changes.
Zhang X, Zhao Y, Shao H, Zheng X
Psychoneuroendocrinology 2019 Oct;108:163-171
Psychoneuroendocrinology 2019 Oct;108:163-171
Gpnmb secreted from liver promotes lipogenesis in white adipose tissue and aggravates obesity and insulin resistance.
Gong XM, Li YF, Luo J, Wang JQ, Wei J, Wang JQ, Xiao T, Xie C, Hong J, Ning G, Shi XJ, Li BL, Qi W, Song BL
Nature metabolism 2019 May;1(5):570-583
Nature metabolism 2019 May;1(5):570-583
Deficiency of heat shock protein A12A promotes browning of white adipose tissues in mice.
Cheng H, Qi T, Zhang X, Kong Q, Min X, Mao Q, Cao X, Liu L, Ding Z
Biochimica et biophysica acta. Molecular basis of disease 2019 Jun 1;1865(6):1451-1459
Biochimica et biophysica acta. Molecular basis of disease 2019 Jun 1;1865(6):1451-1459
Gdf11 gene transfer prevents high fat diet-induced obesity and improves metabolic homeostasis in obese and STZ-induced diabetic mice.
Lu B, Zhong J, Pan J, Yuan X, Ren M, Jiang L, Yang Y, Zhang G, Liu D, Zhang C
Journal of translational medicine 2019 Dec 17;17(1):422
Journal of translational medicine 2019 Dec 17;17(1):422
Identification of a natural beige adipose depot in mice.
Chan M, Lim YC, Yang J, Namwanje M, Liu L, Qiang L
The Journal of biological chemistry 2019 Apr 26;294(17):6751-6761
The Journal of biological chemistry 2019 Apr 26;294(17):6751-6761
Zinc-α2-Glycoprotein Is Associated with Obesity in Chinese People and HFD-Induced Obese Mice.
Liu M, Zhu H, Dai Y, Pan H, Li N, Wang L, Yang H, Yan K, Gong F
Frontiers in physiology 2018;9:62
Frontiers in physiology 2018;9:62
The Protective Effects of Danggui-Baizhu-Tang on High-Fat Diet-Induced Obesity in Mice by Activating Thermogenesis.
Zhao L, Zhu X, Cong R, Yang X, Zhu Y
Frontiers in pharmacology 2018;9:1019
Frontiers in pharmacology 2018;9:1019
Renoprotective Effect of Danhong Injection on Streptozotocin-Induced Diabetic Rats through a Peroxisome Proliferator-Activated Receptor γ Mediated Pathway.
Yang X, Xiao X, Wang H, Li Y, Wang L, Li G, Deng S
Evidence-based complementary and alternative medicine : eCAM 2018;2018:3450141
Evidence-based complementary and alternative medicine : eCAM 2018;2018:3450141
Exosomes From Adipose-Derived Stem Cells Attenuate Adipose Inflammation and Obesity Through Polarizing M2 Macrophages and Beiging in White Adipose Tissue.
Zhao H, Shang Q, Pan Z, Bai Y, Li Z, Zhang H, Zhang Q, Guo C, Zhang L, Wang Q
Diabetes 2018 Feb;67(2):235-247
Diabetes 2018 Feb;67(2):235-247
Antiobesity effect of Lactobacillus reuteri 263 associated with energy metabolism remodeling of white adipose tissue in high-energy-diet-fed rats.
Chen LH, Chen YH, Cheng KC, Chien TY, Chan CH, Tsao SP, Huang HY
The Journal of nutritional biochemistry 2018 Apr;54:87-94
The Journal of nutritional biochemistry 2018 Apr;54:87-94
Green tea extract induces genes related to browning of white adipose tissue and limits weight-gain in high energy diet-fed rat.
Chen LH, Chien YW, Liang CT, Chan CH, Fan MH, Huang HY
Food & nutrition research 2017;61(1):1347480
Food & nutrition research 2017;61(1):1347480
Pdcd4 restrains the self-renewal and white-to-beige transdifferentiation of adipose-derived stem cells.
Bai Y, Shang Q, Zhao H, Pan Z, Guo C, Zhang L, Wang Q
Cell death & disease 2016 Mar 31;7(3):e2169
Cell death & disease 2016 Mar 31;7(3):e2169
Liraglutide suppresses obesity and induces brown fat-like phenotype via Soluble Guanylyl Cyclase mediated pathway in vivo and in vitro.
Zhu E, Yang Y, Zhang J, Li Y, Li C, Chen L, Sun B
Oncotarget 2016 Dec 6;7(49):81077-81089
Oncotarget 2016 Dec 6;7(49):81077-81089
Programmed cell death-4 deficiency prevents diet-induced obesity, adipose tissue inflammation, and insulin resistance.
Wang Q, Dong Z, Liu X, Song X, Song Q, Shang Q, Jiang Y, Guo C, Zhang L
Diabetes 2013 Dec;62(12):4132-43
Diabetes 2013 Dec;62(12):4132-43
Zinc-alpha2-glycoprotein is involved in regulation of body weight through inhibition of lipogenic enzymes in adipose tissue.
Gong FY, Zhang SJ, Deng JY, Zhu HJ, Pan H, Li NS, Shi YF
International journal of obesity (2005) 2009 Sep;33(9):1023-30
International journal of obesity (2005) 2009 Sep;33(9):1023-30
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse brown adipose tissue were subjected to SDS PAGE followed by western blot with 23673-1-AP( UCP1 antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded rat brain using 23673-1-AP( UCP1 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The UCP1 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human UCP1. This antibody recognizes human, mouse antigen. The UCP1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
