UCP1

gene product
SLC25A7, UCP
Mitochondrial uncoupling proteins (UCP) are members of the family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. This gene is expressed only in brown adipose tissue, a specialized tissue which functions to produce heat. [provided by RefSeq, Jul 2008]
More gene data

Featured antibodies

Antibodies

 

Filters

Application

Antibodypedia Validation Initiative

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

Antibody

  or   Clear
Enhanced validation
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Validated within AVI
Eligible for validation within AVI
445 antibodies from 36 providers.

Antibody properties

General

Applications

or Cancel
Antibody
R&D Systems
9 antibodies
Novus Biologicals
37 antibodies
Proteintech Group
1 antibody
antibodies-online
124 antibodies
GeneTex
8 antibodies
Bioss
1 antibody
Invitrogen Antibodies
9 antibodies
NovoPro Bioscience Inc.
8 antibodies
LifeSpan BioSciences, Inc.
67 antibodies
Arigo
3 antibodies
Affinity Biosciences
1 antibody
Biorbyt
36 antibodies
Abnova Corporation
5 antibodies
OriGene
3 antibodies
Abgent
7 antibodies
ProSci
2 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Antibodies.com
1 antibody
Cell Signaling Technology, Inc
1 antibody
NSJ Bioreagents
4 antibodies
Everest Biotech
1 antibody
Aviva Systems Biology
3 antibodies
Creative Biolabs
14 antibodies
MyBioSource
6 antibodies
Boster Biological Technology
2 antibodies
Acris Antibodies GmbH
1 antibody
Rockland Immunochemicals, Inc.
1 antibody
St John's Laboratory
3 antibodies
Creative Diagnostics
6 antibodies
United States Biological
53 antibodies
EMD Millipore
4 antibodies
Leading Biology
7 antibodies
Abbexa
11 antibodies
GenWay
1 antibody
RayBiotech, Inc.
1 antibody
Sigma-Aldrich
3 antibodies