16-5979-82

antibody from Invitrogen Antibodies
Targeting: BTLA BTLA1, CD272
Provider product page for 16-5979-82
Flow cytometry
Other assay

Antibody data

Product number
16-5979-82 - Provider product page
Provider
Invitrogen Antibodies
Product name
CD272 (BTLA) Monoclonal Antibody (MIH26), Functional Grade, eBioscience™
Antibody type
Monoclonal
Antigen
Other
Description
Description: The BTLA monoclonal antibody reacts with human B and T lymphocyte attenuator (BTLA). BTLA is expressed by peripheral lymphocytes, splenic macrophages, developing B cells in the bone marrow and developing T cells in the thymus and mature, but not immature bone marrow-derived dendritic cells. BTLA is implicated as a negative regulator of the activation and/or function of various hemopoietic cell types. It is reported that BTLA binds to B7-H4, but further studies are needed to confirm this interaction. Applications Reported: This MIH26 antibody has been reported for use in flow cytometric analysis. Applications Tested: This MIH26 antibody has been tested by flow cytometric analysis of normal human peripheral blood. This can be used at less than or equal to 0.5 µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Storage and handling: Use in a sterile environment. Filtration: 0.2 µm post-manufacturing filtered. Purity: Greater than 90%, as determined by SDS-PAGE. Endotoxin Level: Less than 0.001 ng/µg antibody, as determined by LAL assay. Aggregation: Less than 10%, as determined by HPLC.
Reactivity
Human
Host
Mouse
Isotype
IgG
Antibody clone number
MIH26
Vial size
100 µg
Concentration
1 mg/mL
Storage
4° C
BTLA protein structure - 16-5979-82 shown in red.