14986-1-AP

antibody from Proteintech Group

Targeting: MGLL HU-K5, MAGL, MGL

Provider product page for 14986-1-AP

Western blot

ELISA

Immunoprecipitation

Immunohistochemistry

Antibody data

Antibody Data
Antigen structure
References [17]
Comments [0]
Validations
Immunohistochemistry [2]

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Product number: 14986-1-AP - Provider product page
Provider: Proteintech Group
Proper citation: Proteintech Cat#14986-1-AP, RRID:AB_2143189
Product name: MGLL antibody
Antibody type: Polyclonal
Description: MGLL antibody (Cat. #14986-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB, ELISA.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

MGLL protein structure - 14986-1-AP shown in red.

Submitted references Atractylodin ameliorates obesity-associated hepatic steatosis by regulating the PLIN2-ATGL/CPT1A axis-mediated lipid droplet-mitochondria interactions.

Chen J, Wei Z, Song Z, Meng S, An J, Zhang Z, Biao Y, Zhang M, Zhang Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jun;155:158134

Inhibition of MAGL ameliorates glucocorticoid-induced bone loss by regulating the Nrf2 signaling.

Huang C, Wang X, Liu S, Xiao P, Lu Z, Xu Y, Tian Y
Free radical biology & medicine 2026 Feb 1;243:67-81

Neonatal supplementation of oleamide during suckling ameliorates maternal postpartum sleep interruption-induced neural impairment and endocannabinoid dysfunction in early adolescent offspring rats.

Qian L, Zheng T, Zhao B, Wang W, Wu Y
Frontiers in nutrition 2025;12:1566182

A galacturonan from sea buckthorn (Hippophae rhamnoides L.) berry modulates dyslipidemia by promoting hepatic lipolysis and mitochondrial oxidation.

Sun Y, Ni W, Wang D, Ren J, Zhao D, Yu S, Liu S, Zhang S, Wang S, Wang W, Liu M
Carbohydrate polymers 2025 Sep 1;363:123708

PRRSV Nsp4 induces ATGL protein degradation to promote viral replication and lipid droplet accumulation.

Xie E, Wang Q, Yi H, Wang J, Liu X, Ye R, Lu L, Tian T, Chen A, Zheng G, Zhang G, Wang H
International journal of biological macromolecules 2025 Jun;312:144097

Qihuang Zhuyu formula modulates mitochondrial function to inhibit platelet activation via endocannabinoid signaling mediated by the SIRT1/PPARα pathway.

Shi R, Sun W, Yin S, Sun T, Yang N, Zhang H, Yao Y, Lai K, Chen X, Yu P
Journal of ethnopharmacology 2025 Feb 10;338(Pt 1):119006

Monoacylglycerol lipase blockades the senescence-associated secretory phenotype by interfering with NF-κB activation and promotes docetaxel efficacy in prostate cancer.

Yu J, Zhang M, Li T, Gao W, Yang Z, Wang K, Liu Z, Zhu S, Wen S, Zhao Y, Cai Q, Shang Z, Wang Y, Niu Y
Oncogene 2024 Sep;43(38):2835-2849

Pea Albumin Alleviates Oleic Acid-Induced Lipid Accumulation in LO2 Cells Through Modulating Lipid Metabolism and Fatty Acid Oxidation Pathways.

Fang B, Luo J, Cui Z, Liu R, Wang P, Zhang J
Foods (Basel, Switzerland) 2024 Oct 30;13(21)

AUP1 transcriptionally activated by KDM5B reprograms lipid metabolism to promote the malignant progression of cervical cancer.

Zhu Y, Yang W, Wang X, Chen M
International journal of oncology 2024 Nov;65(5)

HuR promotes triglyceride synthesis and intestinal fat absorption.

Liu C, Lin Y, Wang Y, Lin S, Zhou J, Tang H, Yi X, Ma Z, Xia T, Jiang B, Tian F, Ju Z, Liu B, Gu X, Yang Z, Wang W
Cell reports 2024 May 28;43(5):114238

Scalp acupuncture alleviates remote hippocampal damage in MCAO rats by inhibiting neuroinflammation: A TMT-based proteomics analysis.

Liu H, Huang W, Ding Q, Huang Y, Lai Z, Liu Z, Li S, Peng X, Wu Z, Deng L, Huang Y, Chen J
Neuroscience 2024 Dec 17;563:117-128

Sleep deprivation induced fat accumulation in the visceral white adipose tissue by suppressing SIRT1/FOXO1/ATGL pathway activation.

Wang W, Liu K, Xu H, Zhang C, Zhang Y, Ding M, Xing C, Huang X, Wen Q, Lu C, Song L
Journal of physiology and biochemistry 2024 Aug;80(3):561-572

TRIM21 attenuates renal carcinoma lipogenesis and malignancy by regulating SREBF1 protein stability.

Chen X, Yong H, Chen M, Deng C, Wang P, Chu S, Li M, Hou P, Zheng J, Li Z, Bai J
Journal of experimental & clinical cancer research : CR 2023 Jan 25;42(1):34

Intermittent hypoxia-induced METTL3 downregulation facilitates MGLL-mediated lipolysis of adipocytes in OSAS.

Huang X, Huang X, Guo H, Li J, Zhou C, Huang Y, Lai C, Zeng W, Tan X, Niu L, Li H, Qi J, Xie C
Cell death discovery 2022 Aug 6;8(1):352

Monoacylglycerol Lipase Knockdown Inhibits Cell Proliferation and Metastasis in Lung Adenocarcinoma.

Zhang H, Guo W, Zhang F, Li R, Zhou Y, Shao F, Feng X, Tan F, Wang J, Gao S, Gao Y, He J
Frontiers in oncology 2020;10:559568

The Endocannabinoid System Contributes to Memory Deficits Induced by Rapid-eye-movement Sleep Deprivation in Adolescent Mice.

Zhang J, Zhang L, Chang Y, Gu Q, Zhang J, Zhu Z, Qian Z, Wei C, Liu Z, Ren W, Han J
Neuroscience 2020 May 1;433:174-183

p21-activated kinase 1 restricts tonic endocannabinoid signaling in the hippocampus.

Xia S, Zhou Z, Leung C, Zhu Y, Pan X, Qi J, Morena M, Hill MN, Xie W, Jia Z
eLife 2016 Jun 14;5

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Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: Immunohistochemical of paraffin-embedded human liver cancer using 14986-1-AP(MGLL antibody) at dilution of 1:100 (under 10x lens)
Sample type: tissue

Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: The MGLL antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human MGLL. This antibody recognizes human,mouse,rat antigen. The MGLL antibody has been validated for the following applications: ELISA, IHC analysis.
Appendix: 14986-1-AP.pdf

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