Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations [0]
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- Product number
- ABIN493460 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Sirtuin 1 (SIRT1) (AA 33-55) antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide corresponding to amino acids 33-55 of Rat Sirtuin-1. Remarks: 100% homology to Mouse and Human Sirtuin-1. The epitope is common in Bovine, Cat, Zebrafish Sirtuin 1 protein.
- Reactivity
- Human, Mouse, Rat, Bovine, Chicken/Avian, Feline
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 mg
- Concentration
- 0.69-0.75 mg/ml (lot. specific)
- Storage
- Store the antibody undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Submitted references SIRT1 is significantly elevated in mouse and human prostate cancer.
Acetylation of the C terminus of Ku70 by CBP and PCAF controls Bax-mediated apoptosis.
Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase.
Mammalian SIRT1 represses forkhead transcription factors.
Huffman DM, Grizzle WE, Bamman MM, Kim JS, Eltoum IA, Elgavish A, Nagy TR
Cancer research 2007 Jul 15;67(14):6612-8
Cancer research 2007 Jul 15;67(14):6612-8
Acetylation of the C terminus of Ku70 by CBP and PCAF controls Bax-mediated apoptosis.
Cohen HY, Lavu S, Bitterman KJ, Hekking B, Imahiyerobo TA, Miller C, Frye R, Ploegh H, Kessler BM, Sinclair DA
Molecular cell 2004 Mar 12;13(5):627-38
Molecular cell 2004 Mar 12;13(5):627-38
Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase.
Yeung F, Hoberg JE, Ramsey CS, Keller MD, Jones DR, Frye RA, Mayo MW
The EMBO journal 2004 Jun 16;23(12):2369-80
The EMBO journal 2004 Jun 16;23(12):2369-80
Mammalian SIRT1 represses forkhead transcription factors.
Motta MC, Divecha N, Lemieux M, Kamel C, Chen D, Gu W, Bultsma Y, McBurney M, Guarente L
Cell 2004 Feb 20;116(4):551-63
Cell 2004 Feb 20;116(4):551-63
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