Tissue expression
Cell line expression
Protein structure

SIRT1

Sirtuin 1
SIR2L1 
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008]
More gene data

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1384 antibodies from 52 providers.

Antibody properties

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AntibodyRefsTypeWBELICCIPIHCFC
Proteintech Group
2 antibodies
Novus Biologicals
51 antibodies
Invitrogen Antibodies
65 antibodies
GeneTex
11 antibodies
antibodies-online
358 antibodies
NSJ Bioreagents
8 antibodies
Abnova Corporation
8 antibodies
OriGene
29 antibodies
Acris Antibodies GmbH
14 antibodies
Bioworld Technology, Inc
1 antibody
Biorbyt
261 antibodies
Boster Biological Technology
8 antibodies
Affinity Biosciences
7 antibodies
Enzo Life Sciences
1 antibody
St John's Laboratory
17 antibodies
Cusabio Biotech Co., Ltd
10 antibodies
Atlas Antibodies
2 antibodies
FineTest Biotech
3 antibodies
HUABIO Research
6 antibodies
Arigo
8 antibodies
NovoPro Bioscience Inc.
5 antibodies
Cell Signaling Technology, Inc
9 antibodies
Abgent
15 antibodies
SignalChem
1 antibody
Everest Biotech
2 antibodies
Aviva Systems Biology
5 antibodies
Antibodies.com
2 antibodies
Exalpha Biologicals, Inc.
1 antibody
R&D Systems
9 antibodies
FabGennix
3 antibodies
RabMAbs
9 antibodies
ProSci
11 antibodies
Bethyl Laboratories
2 antibodies
EMD Millipore
6 antibodies
United States Biological
64 antibodies
MyBioSource
19 antibodies
Abbexa
18 antibodies
Creative Diagnostics
11 antibodies
Abbkine Scientific Co.Ltd.
2 antibodies
Leading Biology
21 antibodies
RayBiotech, Inc.
4 antibodies
Creative Biolabs
58 antibodies
BioLegend
3 antibodies
Active Motif
1 antibody
MilliporeSigma / Merck KGaA
10 antibodies
Abbiotec
2 antibodies
Abiocode, Inc.
1 antibody
GenWay
4 antibodies
Sino Biological Inc.
2 antibodies
Rockland Immunochemicals, Inc.
3 antibodies