Tissue expression
Cell line expression
Protein structure
IRAK3
Interleukin 1 receptor associated kinase 3IRAK-M
This gene encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
Top validated antibodies |
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antibodies-online | ABIN4880793 | Monoclonal |
WB
EL
ICC
IHC
FC
|
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Invitrogen Antibodies | MA5-38545 | Monoclonal |
WB
EL
ICC
IHC
FC
|
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Atlas Antibodies | HPA043097 | Polyclonal |
WB
ICC
IHC
|
||
GeneTex | GTX31265 | Polyclonal |
WB
EL
ICC
IHC |
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LSBio | LS-C368869 | Polyclonal |
WB
ICC
IHC
|
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Supportive data in Antibodypedia
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Recommended by provider