TLX2

This gene is a member of an orphan homeobox-containing transcription factor family. Studies of the mouse ortholog have shown that the encoded protein is crucial for the development of the enteric nervous system; in humans, loss-of-function may play a role in tumorigenesis of gastrointestinal stromal tumors. [provided by RefSeq, May 2010]

Description

T cell leukemia homeobox 2

Protein family

Mapped to neXtProt, Mapped to UniProt SWISS-PROT, Predicted intracellular proteins, Transcription factors

Chromosome

2:p13.1 (74513463 - 74517148)

Ensembl ID

ENSG00000115297  (ver. 99.38)

Orthologs

Mouse Tlx2: ENSMUSG00000068327

UniProt

O43763

neXtProt

NX_O43763

Human splice variants
Mouse splice variants