FAM189B

This gene is located near the gene for the lysosomal enzyme glucosylceramidase; a deficiency in this enzyme is associated with Gaucher disease. The encoded protein has been identified as a potential binding partner of a WW domain-containing protein which is involved in apoptosis and tumor suppression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2010]

Description

family with sequence similarity 189 member B

Protein family

Mapped to neXtProt, Mapped to UniProt SWISS-PROT, Predicted membrane proteins, Protein evidence (Peptideatlas)

Chromosome

1:q22 (155247205 - 155255483)

Ensembl ID

ENSG00000160767  (ver. 99.38)

Orthologs

Mouse Fam189b: ENSMUSG00000032657

UniProt

P81408

neXtProt

NX_P81408

Human splice variants
Mouse splice variants