ABIN350025

antibody from antibodies-online

Targeting: LMNA CMD1A, HGPS, LGMD1B, LMN1, LMNL1, MADA, PRO1

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN350025

Provider

antibodies-online

Proper citation

Antibodies-Online Cat#ABIN350025, RRID:AB_10781867

Product name

anti-Homer Homolog 1 (Drosophila) (HOMER1) (Internal Region) antibody

Antibody type

Polyclonal

Antigen

A synthetic peptide from the internal region of human HOMER1 (Home1, Homer protein homolog 1, SYN47) conjugated to an immunogenic carrier protein was used as the antigen. The peptide is homologous in mouse, rat, monkey and xenopus.

Description

Immunoaffinity purification

Reactivity

Human, Mouse, Rat

Host

Rabbit

Epitope

Internal Region

Vial size

100 μL

Storage

Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability.

Handling

Avoid freeze and thaw cycles.

References

Submitted references

Homer1c interacts with Hippi and protects striatal neurons from apoptosis.

Sakamoto K, Yoshida S, Ikegami K, Minakami R, Kato A, Udo H, Sugiyama H
Biochemical and biophysical research communications 2007 Jan 5;352(1):1-5

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Homer proteins and InsP(3) receptors co-localise in the longitudinal sarcoplasmic reticulum of skeletal muscle fibres.

Salanova M, Priori G, Barone V, Intravaia E, Flucher B, Ciruela F, McIlhinney RA, Parys JB, Mikoshiba K, Sorrentino V
Cell calcium 2002 Oct;32(4):193-200

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Crystal structure of the Homer 1 family conserved region reveals the interaction between the EVH1 domain and own proline-rich motif.

Irie K, Nakatsu T, Mitsuoka K, Miyazawa A, Sobue K, Hiroaki Y, Doi T, Fujiyoshi Y, Kato H
Journal of molecular biology 2002 May 10;318(4):1117-26

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An N-terminal sequence specific for a novel Homer1 isoform controls trafficking of group I metabotropic glutamate receptor in mammalian cells.

Saito H, Kimura M, Inanobe A, Ohe T, Kurachi Y
Biochemical and biophysical research communications 2002 Aug 23;296(3):523-9

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Homer: a link between neural activity and glutamate receptor function.

Xiao B, Tu JC, Worley PF
Current opinion in neurobiology 2000 Jun;10(3):370-4

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Homer 1b regulates the trafficking of group I metabotropic glutamate receptors.

Roche KW, Tu JC, Petralia RS, Xiao B, Wenthold RJ, Worley PF
The Journal of biological chemistry 1999 Sep 3;274(36):25953-7

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Homer binds a novel proline-rich motif and links group 1 metabotropic glutamate receptors with IP3 receptors.

Tu JC, Xiao B, Yuan JP, Lanahan AA, Leoffert K, Li M, Linden DJ, Worley PF
Neuron 1998 Oct;21(4):717-26

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Homer regulates the association of group 1 metabotropic glutamate receptors with multivalent complexes of homer-related, synaptic proteins.

Xiao B, Tu JC, Petralia RS, Yuan JP, Doan A, Breder CD, Ruggiero A, Lanahan AA, Wenthold RJ, Worley PF
Neuron 1998 Oct;21(4):707-16

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vesl, a gene encoding VASP/Ena family related protein, is upregulated during seizure, long-term potentiation and synaptogenesis.

Kato A, Ozawa F, Saitoh Y, Hirai K, Inokuchi K
FEBS letters 1997 Jul 21;412(1):183-9