LMNA

gene product
CMD1A, HGPS, LGMD1B, LMN1, LMNL1, PRO1
The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Alternative splicing results in multiple transcript variants. Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome. [provided by RefSeq, Apr 2012]
More gene data

Featured antibodies

Antibodies

 

Filters

Antibodypedia Validation Initiative

Validation method

Application

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

  or   Clear
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Validated within AVI
Eligible for validation within AVI
1065 antibodies from 45 providers.

Antibody properties

Applications

or Cancel
AntibodyRefsTypeAVIWBELICCIPIHCFC
GeneTex
21 antibodies
Novus Biologicals
123 antibodies
Invitrogen Antibodies
18 antibodies
Abnova Corporation
16 antibodies
Boster Biological Technology
3 antibodies
Cell Signaling Technology, Inc
11 antibodies
antibodies-online
270 antibodies
NovoPro Bioscience Inc.
13 antibodies
Proteintech Group
1 antibody
Biorbyt
55 antibodies
Aviva Systems Biology
8 antibodies
LifeSpan BioSciences, Inc.
155 antibodies
Affinity Biosciences
5 antibodies
Bethyl Laboratories
4 antibodies
OriGene
65 antibodies