ABIN112042

antibody from antibodies-online

Targeting: LMNA CMD1A, HGPS, LGMD1B, LMN1, LMNL1, MADA, PRO1

Western blot (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Antibody Data

Product number

ABIN112042

Provider

antibodies-online

Product name

anti-Lamin A/C (LMNA) antibody

Antibody type

Monoclonal

Description

Purified

Reactivity

Human, Mouse, Rat, Bovine, Canine

Host

Mouse

Isotype

IgG

Antibody clone number

133A2

Vial size

0.1 mg

Storage

Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.

Handling

Avoid repeated freezing and thawing.

References

Submitted references

Recurrent de novo point mutations in lamin A cause Hutchinson-Gilford progeria syndrome.

Eriksson M, Brown WT, Gordon LB, Glynn MW, Singer J, Scott L, Erdos MR, Robbins CM, Moses TY, Berglund P, Dutra A, Pak E, Durkin S, Csoka AB, Boehnke M, Glover TW, Collins FS
Nature 2003 May 15;423(6937):293-8

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Lamin a truncation in Hutchinson-Gilford progeria.

De Sandre-Giovannoli A, Bernard R, Cau P, Navarro C, Amiel J, Boccaccio I, Lyonnet S, Stewart CL, Munnich A, Le Merrer M, Lévy N
Science (New York, N.Y.) 2003 Jun 27;300(5628):2055

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Partial cleavage of A-type lamins concurs with their total disintegration from the nuclear lamina during apoptosis.

Broers JL, Bronnenberg NM, Kuijpers HJ, Schutte B, Hutchison CJ, Ramaekers FC
European journal of cell biology 2002 Dec;81(12):677-91

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Dynamics of the nuclear lamina as monitored by GFP-tagged A-type lamins.

Broers JL, Machiels BM, van Eys GJ, Kuijpers HJ, Manders EM, van Driel R, Ramaekers FC
Journal of cell science 1999 Oct;112 ( Pt 20):3463-75

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Spatial distribution of lamin A and B1 in the K562 cell nuclear matrix stabilized with metal ions.

Neri LM, Raymond Y, Giordano A, Borgatti P, Marchisio M, Capitani S, Martelli AM
Journal of cellular biochemistry 1999 Oct 1;75(1):36-45

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Lamin A is part of the internal nucleoskeleton of human erythroleukemia cells.

Neri LM, Raymond Y, Giordano A, Capitani S, Martelli AM
Journal of cellular physiology 1999 Mar;178(3):284-95

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Comparison of A and B-type lamin expression in reactive lymph nodes and nodular sclerosing Hodgkin's disease.

Jansen MP, Machiels BM, Hopman AH, Broers JL, Bot FJ, Arends JW, Ramaekers FC, Schouten HC
Histopathology 1997 Oct;31(4):304-12

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Distinct nuclear assembly pathways for lamins A and C lead to their increase during quiescence in Swiss 3T3 cells.

Pugh GE, Coates PJ, Lane EB, Raymond Y, Quinlan RA
Journal of cell science 1997 Oct;110 ( Pt 19):2483-93

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Nuclear lamin expression in normal testis and testicular germ cell tumours of adolescents and adults.

Machiels BM, Ramaekers FC, Kuijpers HJ, Groenewoud JS, Oosterhuis JW, Looijenga LH
The Journal of pathology 1997 Jun;182(2):197-204

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A- and B-type lamins are differentially expressed in normal human tissues.

Broers JL, Machiels BM, Kuijpers HJ, Smedts F, van den Kieboom R, Raymond Y, Ramaekers FC
Histochemistry and cell biology 1997 Jun;107(6):505-17

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Lamin proteins form an internal nucleoskeleton as well as a peripheral lamina in human cells.

Hozák P, Sasseville AM, Raymond Y, Cook PR
Journal of cell science 1995 Feb;108 ( Pt 2):635-44

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Abnormal A-type lamin organization in a human lung carcinoma cell line.

Machiels BM, Broers JL, Raymond Y, de Ley L, Kuijpers HJ, Caberg NE, Ramaekers FC
European journal of cell biology 1995 Aug;67(4):328-35