NBP1-50051
antibody from Novus Biologicals
Targeting: LMNA
CMD1A, HGPS, LGMD1B, LMN1, LMNL1, MADA, PRO1
Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Western blot [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- NBP1-50051 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NBP1-50051, RRID:AB_10012241
- Product name
- Mouse Monoclonal Lamin A + C Antibody
- Antibody type
- Monoclonal
- Description
- Protein A purified. The mouse monoclonal antibody EM-11 recognizes lamin C, intermediate filament protein of nuclear lamina.
- Reactivity
- Human, Mouse
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.1 mg
- Concentration
- 1 mg/ml
- Storage
- Store at 4C. Do not freeze.
Submitted references Nuclear re-localization of Dicer in primary mouse embryonic fibroblast nuclei following DNA damage.
Structural organization of nuclear lamins A, C, B1, and B2 revealed by superresolution microscopy.
Burger K, Gullerova M
PLoS genetics 2018 Feb;14(2):e1007151
PLoS genetics 2018 Feb;14(2):e1007151
Structural organization of nuclear lamins A, C, B1, and B2 revealed by superresolution microscopy.
Shimi T, Kittisopikul M, Tran J, Goldman AE, Adam SA, Zheng Y, Jaqaman K, Goldman RD
Molecular biology of the cell 2015 Nov 5;26(22):4075-86
Molecular biology of the cell 2015 Nov 5;26(22):4075-86
No comments: Submit comment
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: Lamin A + C Antibody (EM-11) [NBP1-50051] - Immunoblots detecting total HA-Dicer (C29F4, HA.11, 3F10) in subcellular fractions of PMEF: HA-Dicer cells. CP and NP fractions were loaded in a 1:3 ratio. HA signals were quantified using ImageJ. CTD S2P, RNA polymerase II carboxy-terminal domain (CTD) phospho-residue serine2; Rad21, cohesin subunit; KDEL motif recognising Grp94/Grp78; H3, histone H3. Image collected and cropped by CiteAb from the following publication (journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1007151), licensed under a CC-BY licence.