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- References [13]
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- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [2]
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- Product number
- 14905-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14905-1-AP, RRID:AB_2172484
- Product name
- PSMC2 antibody
- Antibody type
- Polyclonal
- Description
- PSMC2 antibody (Cat. #14905-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Curcumin modulates β-catenin stabilization via targeting proteasomal deubiquitinating enzyme USP14(☆).
Prognostic Signature in Osteosarcoma Based on Amino Acid Metabolism-Associated Genes.
Quantitative mapping of proteasome interactomes and substrates using ProteasomeID.
Tianhe Zhuifeng Gao reverses inflammatory response and attenuates bone/cartilage destruction in rheumatoid arthritis via PSMC2-RUNX2-COL1A1 axis based on transcriptional regulatory network analysis and experimental validation.
Proteomic Characterization Identifies Clinically Relevant Subgroups of Gastrointestinal Stromal Tumors.
Zonisamide attenuates pressure overload-induced myocardial hypertrophy in mice through proteasome inhibition.
PSMC2 is a Novel Prognostic Biomarker and Predicts Immunotherapeutic Responses: From Pancreatic Cancer to Pan-Cancer.
PSMC2 knockdown exerts an anti-tumor role in nasopharyngeal carcinoma through regulating AKT signaling pathway.
Silencing Proteasome 26S Subunit ATPase 2 (PSMC2) Protects the Osteogenic Differentiation In Vitro and Osteogenesis In Vivo.
PSMC2, ORC5 and KRTDAP are specific biomarkers for HPV-negative head and neck squamous cell carcinoma.
PDLIM7 Synergizes With PDLIM2 and p62/Sqstm1 to Inhibit Inflammatory Signaling by Promoting Degradation of the p65 Subunit of NF-κB.
Differentially expressed proteins identified by TMT proteomics analysis in bone marrow microenvironment of osteoporotic patients.
Quercetin Prevents In Vivo and In Vitro Myocardial Hypertrophy Through the Proteasome-GSK-3 Pathway.
Shen M, Chen L, Jiang J, Wang Z, Gong Q, Zhang X, Ke X, Qu Y
Pharmacological research 2025 Jun;216:107745
Pharmacological research 2025 Jun;216:107745
Prognostic Signature in Osteosarcoma Based on Amino Acid Metabolism-Associated Genes.
Feng L, Chen Y, Mei X, Wang L, Zhao W, Yao J
Cancer biotherapy & radiopharmaceuticals 2024 Sep;39(7):517-531
Cancer biotherapy & radiopharmaceuticals 2024 Sep;39(7):517-531
Quantitative mapping of proteasome interactomes and substrates using ProteasomeID.
Bartolome A, Heiby JC, Di Fraia D, Heinze I, Knaudt H, Spaeth E, Omrani O, Minetti A, Hofmann M, Kirkpatrick JM, Dau T, Ori A
eLife 2024 Sep 4;13
eLife 2024 Sep 4;13
Tianhe Zhuifeng Gao reverses inflammatory response and attenuates bone/cartilage destruction in rheumatoid arthritis via PSMC2-RUNX2-COL1A1 axis based on transcriptional regulatory network analysis and experimental validation.
Liu X, Mao X, Chen W, Zhang Y, Li T, Wang K, Lin N, Zhang Y
International immunopharmacology 2024 Sep 10;138:112573
International immunopharmacology 2024 Sep 10;138:112573
Proteomic Characterization Identifies Clinically Relevant Subgroups of Gastrointestinal Stromal Tumors.
Sun M, Tong Y, Yuan W, Wang Y, Pu Y, Huang W, Lv B, Xu C, Jiang W, Luo R, Fang R, Tang S, Ren L, Wang J, Feng J, Sun C, Shen K, He F, Hou Y, Ding C
Gastroenterology 2024 Mar;166(3):450-465.e33
Gastroenterology 2024 Mar;166(3):450-465.e33
Zonisamide attenuates pressure overload-induced myocardial hypertrophy in mice through proteasome inhibition.
Wu Q, Liu WJ, Ma XY, Chang JS, Zhao XY, Liu YH, Yu XY
Acta pharmacologica Sinica 2024 Apr;45(4):738-750
Acta pharmacologica Sinica 2024 Apr;45(4):738-750
PSMC2 is a Novel Prognostic Biomarker and Predicts Immunotherapeutic Responses: From Pancreatic Cancer to Pan-Cancer.
Huang W, Qian Z, Shi Y, Zhang Z, Hou R, Mei J, Xu J, Ding J
Pharmacogenomics and personalized medicine 2023;16:747-758
Pharmacogenomics and personalized medicine 2023;16:747-758
PSMC2 knockdown exerts an anti-tumor role in nasopharyngeal carcinoma through regulating AKT signaling pathway.
Su J, Hu S, Ding S, Feng K
Cell cycle (Georgetown, Tex.) 2023 Nov;22(21-22):2381-2391
Cell cycle (Georgetown, Tex.) 2023 Nov;22(21-22):2381-2391
Silencing Proteasome 26S Subunit ATPase 2 (PSMC2) Protects the Osteogenic Differentiation In Vitro and Osteogenesis In Vivo.
Zhou B, Peng K, Wang G, Chen W, Kang Y
Calcified tissue international 2021 Jul;109(1):44-54
Calcified tissue international 2021 Jul;109(1):44-54
PSMC2, ORC5 and KRTDAP are specific biomarkers for HPV-negative head and neck squamous cell carcinoma.
Su Y, Zeng Z, Rong D, Yang Y, Wu B, Cao Y
Oncology letters 2021 Apr;21(4):289
Oncology letters 2021 Apr;21(4):289
PDLIM7 Synergizes With PDLIM2 and p62/Sqstm1 to Inhibit Inflammatory Signaling by Promoting Degradation of the p65 Subunit of NF-κB.
Jodo A, Shibazaki A, Onuma A, Kaisho T, Tanaka T
Frontiers in immunology 2020;11:1559
Frontiers in immunology 2020;11:1559
Differentially expressed proteins identified by TMT proteomics analysis in bone marrow microenvironment of osteoporotic patients.
Zhou Q, Xie F, Zhou B, Wang J, Wu B, Li L, Kang Y, Dai R, Jiang Y
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 2019 May;30(5):1089-1098
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 2019 May;30(5):1089-1098
Quercetin Prevents In Vivo and In Vitro Myocardial Hypertrophy Through the Proteasome-GSK-3 Pathway.
Chen K, Rekep M, Wei W, Wu Q, Xue Q, Li S, Tian J, Yi Q, Zhang G, Zhang G, Xiao Q, Luo J, Liu Y
Cardiovascular drugs and therapy 2018 Feb;32(1):5-21
Cardiovascular drugs and therapy 2018 Feb;32(1):5-21
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human adrenal gland tissue were subjected to SDS PAGE followed by western blot with 14905-1-AP(PSMC2 antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of MCF-7 cells, using PSMC2 antibody 14905-1-AP at 1:50 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human ovary tumor using 14905-1-AP(PSMC2 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human ovary tumor using 14905-1-AP(PSMC2 antibody) at dilution of 1:100 (under 40x lens)
- Sample type
- tissue
