Explore
Validate
Learn13828-1-AP
antibody from Proteintech Group
Targeting: ATP6V0A1
a1, ATP6N1, ATP6N1A, Stv1, Vph1, VPP1
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [16]
- Comments [0]
- Validations [0]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 13828-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- ATP6V0A1 antibody
- Antibody type
- Polyclonal
- Description
- ATP6V0A1 antibody (Cat. #13828-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Rab14 restricts pathogens by promoting V-ATPase lysosomal delivery to drive lysosomal acidification.
Oral Exposure to Food-Grade Nanoparticles Poses a Risk of Alzheimer's Disease-Like Symptoms by Triggering Autophagy Defects in Neurons.
Cadmium-induced ATP6V0A1 destabilization impairs lysosomal function to disrupt hepatic lipid homeostasis.
A heterotrimeric protein complex assembles the metazoan V-ATPase upon dissipation of proton gradients.
Oxr1 and Ncoa7 regulate V-ATPase to achieve optimal pH for glycosylation within the Golgi apparatus and trans-Golgi network.
ATP6V0A1-dependent cholesterol absorption in colorectal cancer cells triggers immunosuppressive signaling to inactivate memory CD8(+) T cells.
Osmundacetone ameliorates Alzheimer's-like pathologies by inhibiting β-amyloid fibrillation, oxidative damage and neuroinflammation in APP/PS1 transgenic mice.
Golgi pH elevation due to loss of V-ATPase subunit V0a2 function correlates with tissue-specific glycosylation changes and globozoospermia.
The V-ATPase/ATG16L1 axis is controlled by the V(1)H subunit.
ATP6V0D1 promotes alkaliptosis by blocking STAT3-mediated lysosomal pH homeostasis.
Toosendanin, a novel potent vacuolar-type H(+)-translocating ATPase inhibitor, sensitizes cancer cells to chemotherapy by blocking protective autophagy.
The Ncoa7 locus regulates V-ATPase formation and function, neurodevelopment and behaviour.
Systematic deletion of adenosine receptors reveals novel roles in inflammation and pyroptosis in THP-1 macrophages.
TRPM2 promotes autophagic degradation in vascular smooth muscle cells.
PDK4 promotes vascular calcification by interfering with autophagic activity and metabolic reprogramming.
A pH-sensitive luminal His-cluster promotes interaction of PAM with V-ATPase along the secretory and endocytic pathways of peptidergic cells.
Lei Z, Qiang L, Ge P, Qiang Y, Sun T, Chai Q, Wang Y, Lv S, Qiu C, Lu Z, Zhao M, Zhao Z, Wu Y, Zhang X, Zhong Y, Li B, Zhang L, Wang J, Liu CH
Nature communications 2026 Mar 2;17(1)
Nature communications 2026 Mar 2;17(1)
Oral Exposure to Food-Grade Nanoparticles Poses a Risk of Alzheimer's Disease-Like Symptoms by Triggering Autophagy Defects in Neurons.
Shang J, Yan J, Lou H, Jiang X, Wang Z, Gao Y, Fan X, Lu X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Jan;13(3):e08096
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Jan;13(3):e08096
Cadmium-induced ATP6V0A1 destabilization impairs lysosomal function to disrupt hepatic lipid homeostasis.
Huo J, Li K, Shi H, Liu Y, Gu J
Biochimica et biophysica acta. Molecular and cell biology of lipids 2026 Apr;1871(3):159733
Biochimica et biophysica acta. Molecular and cell biology of lipids 2026 Apr;1871(3):159733
A heterotrimeric protein complex assembles the metazoan V-ATPase upon dissipation of proton gradients.
Nardone C, Mintseris J, He D, Rutter JC, Ebert BL, Gygi SP, Rapoport T
Nature structural & molecular biology 2025 Oct;32(10):2076-2087
Nature structural & molecular biology 2025 Oct;32(10):2076-2087
Oxr1 and Ncoa7 regulate V-ATPase to achieve optimal pH for glycosylation within the Golgi apparatus and trans-Golgi network.
Yoshimura SI, Sobajima T, Kunii M, Harada A
Proceedings of the National Academy of Sciences of the United States of America 2025 Jun 3;122(22):e2505975122
Proceedings of the National Academy of Sciences of the United States of America 2025 Jun 3;122(22):e2505975122
ATP6V0A1-dependent cholesterol absorption in colorectal cancer cells triggers immunosuppressive signaling to inactivate memory CD8(+) T cells.
Huang TX, Huang HS, Dong SW, Chen JY, Zhang B, Li HH, Zhang TT, Xie Q, Long QY, Yang Y, Huang LY, Zhao P, Bi J, Lu XF, Pan F, Zou C, Fu L
Nature communications 2024 Jul 6;15(1):5680
Nature communications 2024 Jul 6;15(1):5680
Osmundacetone ameliorates Alzheimer's-like pathologies by inhibiting β-amyloid fibrillation, oxidative damage and neuroinflammation in APP/PS1 transgenic mice.
Zhao LX, Ren H, Su JY, Zhang Q, He DL, Wu TY, Zhang YH, Wang ZY, Fan YG
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156091
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156091
Golgi pH elevation due to loss of V-ATPase subunit V0a2 function correlates with tissue-specific glycosylation changes and globozoospermia.
Kopp J, Jahn D, Vogt G, Psoma A, Ratto E, Morelle W, Stelzer N, Hausser I, Hoffmann A, de Los Santos MR, Koch LA, Fischer-Zirnsak B, Thiel C, Palm W, Meierhofer D, van den Bogaart G, Foulquier F, Meinhardt A, Kornak U
Cellular and molecular life sciences : CMLS 2024 Dec 16;82(1):4
Cellular and molecular life sciences : CMLS 2024 Dec 16;82(1):4
The V-ATPase/ATG16L1 axis is controlled by the V(1)H subunit.
Timimi L, Wrobel AG, Chiduza GN, Maslen SL, Torres-Méndez A, Montaner B, Davis C, Minckley T, Hole KL, Serio A, Devine MJ, Skehel JM, Rubinstein JL, Schreiber A, Beale R
Molecular cell 2024 Aug 8;84(15):2966-2983.e9
Molecular cell 2024 Aug 8;84(15):2966-2983.e9
ATP6V0D1 promotes alkaliptosis by blocking STAT3-mediated lysosomal pH homeostasis.
Chen F, Zhu S, Kang R, Tang D, Liu J
Cell reports 2023 Jan 31;42(1):111911
Cell reports 2023 Jan 31;42(1):111911
Toosendanin, a novel potent vacuolar-type H(+)-translocating ATPase inhibitor, sensitizes cancer cells to chemotherapy by blocking protective autophagy.
Dong Y, Zhu G, Wang SF, Keon KA, Rubinstein JL, Zeng SX, Zhang S, Chen QL, Fu J, Li M, Shen HM, Lu JJ, Chen XP, Lu JH
International journal of biological sciences 2022;18(7):2684-2702
International journal of biological sciences 2022;18(7):2684-2702
The Ncoa7 locus regulates V-ATPase formation and function, neurodevelopment and behaviour.
Castroflorio E, den Hoed J, Svistunova D, Finelli MJ, Cebrian-Serrano A, Corrochano S, Bassett AR, Davies B, Oliver PL
Cellular and molecular life sciences : CMLS 2021 Apr;78(7):3503-3524
Cellular and molecular life sciences : CMLS 2021 Apr;78(7):3503-3524
Systematic deletion of adenosine receptors reveals novel roles in inflammation and pyroptosis in THP-1 macrophages.
Eudy BJ, da Silva RP
Molecular immunology 2021 Apr;132:1-7
Molecular immunology 2021 Apr;132:1-7
TRPM2 promotes autophagic degradation in vascular smooth muscle cells.
Zhao Q, Li J, Ko WH, Kwan YW, Jiang L, Sun L, Yao X
Scientific reports 2020 Nov 26;10(1):20719
Scientific reports 2020 Nov 26;10(1):20719
PDK4 promotes vascular calcification by interfering with autophagic activity and metabolic reprogramming.
Ma WQ, Sun XJ, Zhu Y, Liu NF
Cell death & disease 2020 Nov 17;11(11):991
Cell death & disease 2020 Nov 17;11(11):991
A pH-sensitive luminal His-cluster promotes interaction of PAM with V-ATPase along the secretory and endocytic pathways of peptidergic cells.
Rao VK, Zavala G, Deb Roy A, Mains RE, Eipper BA
Journal of cellular physiology 2019 Jun;234(6):8683-8697
Journal of cellular physiology 2019 Jun;234(6):8683-8697
No comments: Submit comment
No validations: Submit validation data