ATP6V0A1

gene product
a1, ATP6N1, ATP6N1A, Stv1, Vph1, VPP1
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c"", and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene encodes one of three A subunit proteins and the encoded protein is associated with clathrin-coated vesicles. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
More gene data

Featured antibodies

Antibodies

 

Filters

Application

Antibodypedia Validation Initiative

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

Antibody

  or   Clear
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Validated within AVI
Eligible for validation within AVI
95 antibodies from 17 providers.

Antibody properties

General

Applications

or Cancel
AntibodyRefsTypeWBELICCIPIHCFC
Novus Biologicals
3 antibodies
antibodies-online
28 antibodies
Aviva Systems Biology
3 antibodies
Abgent
1 antibody
Atlas Antibodies
1 antibody
LifeSpan BioSciences, Inc.
16 antibodies
GeneTex
2 antibodies
Biorbyt
12 antibodies
Acris Antibodies GmbH
1 antibody
Invitrogen Antibodies
3 antibodies
OriGene
2 antibodies
MyBioSource
2 antibodies
United States Biological
13 antibodies
St John's Laboratory
1 antibody
Creative Diagnostics
3 antibodies
Sigma-Aldrich
2 antibodies
Abnova Corporation
2 antibodies