LGMN

gene product
LGMN1, PRSC1
This gene encodes a cysteine protease that has a strict specificity for hydrolysis of asparaginyl bonds. This enzyme may be involved in the processing of bacterial peptides and endogenous proteins for MHC class II presentation in the lysosomal/endosomal systems. Enzyme activation is triggered by acidic pH and appears to be autocatalytic. Protein expression occurs after monocytes differentiate into dendritic cells. A fully mature, active enzyme is produced following lipopolysaccharide expression in mature dendritic cells. Overexpression of this gene may be associated with the majority of solid tumor types. This gene has a pseudogene on chromosome 13. Several alternatively spliced transcript variants have been described, but the biological validity of only two has been determined. These two variants encode the same isoform. [provided by RefSeq, Jul 2008]
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214 antibodies from 23 providers.

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AntibodyRefsTypeAVIWBELICCIPIHCFC
R&D Systems
6 antibodies
Novus Biologicals
27 antibodies
Atlas Antibodies
2 antibodies
antibodies-online
43 antibodies
NovoPro Bioscience Inc.
5 antibodies
Biorbyt
4 antibodies
Abnova Corporation
7 antibodies
LifeSpan BioSciences, Inc.
63 antibodies
GeneTex
2 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Cell Signaling Technology, Inc
1 antibody
Aviva Systems Biology
3 antibodies
MyBioSource
4 antibodies
OriGene
2 antibodies
Invitrogen Antibodies
4 antibodies
Abgent
3 antibodies
Creative Diagnostics
6 antibodies
St John's Laboratory
2 antibodies
ProSci
1 antibody
Sigma-Aldrich
2 antibodies
United States Biological
13 antibodies
Creative Biolabs
1 antibody