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- References [8]
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- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [2]
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- Product number
- 14311-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14311-1-AP, RRID:AB_2290777
- Product name
- Caspase 10/p23/17/p12 antibody
- Antibody type
- Polyclonal
- Description
- Caspase 10/p23/17/p12 antibody (Cat. #14311-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references HIF-activated priming of TRAIL-induced cell death determines epigenetic vulnerability in kidney cancer.
Altered Bcl-2/Caspase signaling and hypoxia-induced apoptosis in primary human aniridia limbal stromal cells, in CoCl2 mediated hypoxic stress, in vitro.
A non-apoptotic caspase-8-meteorin pathway in hepatocytes promotes MASH fibrosis.
CircRNA-mediated ceRNA network: micron-sized quartz silica particles induce apoptosis in primary human airway epithelial cells.
Strong activation of p53 by actinomycin D and nutlin-3a overcomes the resistance of cancer cells to the pro-apoptotic activity of the FAS ligand.
Hyperactivation of SREBP induces pannexin-1-dependent lytic cell death.
Enterovirus 71 Induces INF2 Cleavage via Activated Caspase-2 in Infected RD Cells.
A New Chalcone Derivative C49 Reverses Doxorubicin Resistance in MCF-7/DOX Cells by Inhibiting P-Glycoprotein Expression.
Wang Y, Xiong Y, Liu S, Bao L, Qiu X, Korboukh I, Song X, Toffessi Tcheuyap V, Wu S, Chen M, Brugarolas J, Jin J, Wang Y, Luo W
Cell reports. Medicine 2026 Mar 17;7(3):102630
Cell reports. Medicine 2026 Mar 17;7(3):102630
Altered Bcl-2/Caspase signaling and hypoxia-induced apoptosis in primary human aniridia limbal stromal cells, in CoCl2 mediated hypoxic stress, in vitro.
Liu S, Li S, Hsu SL, Fries FN, Li Z, Kundu S, Seitz B, Amini M, Suiwal S, Zimmermann J, Trusen S, Stachon T, Szentmáry N
PloS one 2025;20(7):e0328157
PloS one 2025;20(7):e0328157
A non-apoptotic caspase-8-meteorin pathway in hepatocytes promotes MASH fibrosis.
Wang X, Moore MP, Shi H, Xiao Y, Zhang J, Faccioli LAP, Hu Z, Khalid S, Saleheen D, Stupack DG, Kisseleva T, Soto Gutierrez A, Lazar MA, Tabas I
Nature metabolism 2025 Oct;7(10):2067-2082
Nature metabolism 2025 Oct;7(10):2067-2082
CircRNA-mediated ceRNA network: micron-sized quartz silica particles induce apoptosis in primary human airway epithelial cells.
Ma J, Han B, Yang Y, Zhang Y, Cao M, Cao W, Zhang W, Cheng M, Cui G, Du Z, Chen S
Toxicology mechanisms and methods 2025 Nov;35(9):1419-1436
Toxicology mechanisms and methods 2025 Nov;35(9):1419-1436
Strong activation of p53 by actinomycin D and nutlin-3a overcomes the resistance of cancer cells to the pro-apoptotic activity of the FAS ligand.
Łasut-Szyszka B, Gdowicz-Kłosok A, Krześniak M, Głowala-Kosińska M, Będzińska A, Rusin M
Apoptosis : an international journal on programmed cell death 2024 Oct;29(9-10):1515-1528
Apoptosis : an international journal on programmed cell death 2024 Oct;29(9-10):1515-1528
Hyperactivation of SREBP induces pannexin-1-dependent lytic cell death.
Xiong Y, Luo J, Hong ZY, Zhu WZ, Hu A, Song BL
Journal of lipid research 2024 Jul;65(7):100579
Journal of lipid research 2024 Jul;65(7):100579
Enterovirus 71 Induces INF2 Cleavage via Activated Caspase-2 in Infected RD Cells.
Wang B, Zhang C, Yu C, Zhu Y, Tang Q, Huang H, Zhao Z
Frontiers in microbiology 2021;12:684953
Frontiers in microbiology 2021;12:684953
A New Chalcone Derivative C49 Reverses Doxorubicin Resistance in MCF-7/DOX Cells by Inhibiting P-Glycoprotein Expression.
Wang T, Dong J, Yuan X, Wen H, Wu L, Liu J, Sui H, Deng W
Frontiers in pharmacology 2021;12:653306
Frontiers in pharmacology 2021;12:653306
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 14311-1-AP(CASP10 antibody) at dilution of 1:300
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using CASP10 antibody 14311-1-AP at 1:50 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human endometrial cancer using 14311-1-AP(CASP10 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human endometrial cancer using 14311-1-AP(CASP10 antibody) at dilution of 1:100 (under 40x lens)
- Sample type
- tissue
