Tissue expression
Cell line expression

CASP10

gene product
FLICE-2, MCH4 
This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in this gene are associated with type IIA autoimmune lymphoproliferative syndrome, non-Hodgkin lymphoma and gastric cancer. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Apr 2011]
More gene data

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618 antibodies from 46 providers.

Antibody properties

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AntibodyRefsTypeWBELICCIPIHCFC
Proteintech Group
1 antibody
antibodies-online
207 antibodies
GeneTex
8 antibodies
Novus Biologicals
13 antibodies
LifeSpan BioSciences, Inc.
79 antibodies
OriGene
14 antibodies
NovoPro Bioscience Inc.
1 antibody
Wuhan Fine Biotech Co., Ltd.
1 antibody
Biorbyt
44 antibodies
Acris Antibodies GmbH
18 antibodies
Aviva Systems Biology
4 antibodies
Cusabio Biotech Co., Ltd
9 antibodies
Boster Biological Technology
5 antibodies
Abnova Corporation
10 antibodies
Abgent
8 antibodies
Affinity Biosciences
2 antibodies
HUABIO Research
1 antibody
Invitrogen Antibodies
20 antibodies
Bioworld Technology, Inc
3 antibodies
R&D Systems
3 antibodies
NSJ Bioreagents
2 antibodies
Atlas Antibodies
1 antibody
RabMAbs
2 antibodies
Enzo Life Sciences
1 antibody
St John's Laboratory
4 antibodies
Arigo
4 antibodies
MyBioSource
11 antibodies
Creative Diagnostics
6 antibodies
Abbiotec
2 antibodies
RayBiotech, Inc.
2 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
BioLegend
1 antibody
United States Biological
67 antibodies
Spring Bioscience
4 antibodies
Abbexa
11 antibodies
GenWay
5 antibodies
Leading Biology
2 antibodies
Abiocode, Inc.
1 antibody
ProSci
1 antibody
QED Bioscience
1 antibody
Creative Biolabs
14 antibodies
MilliporeSigma / Merck KGaA
4 antibodies
EMD Millipore
2 antibodies
Exalpha Biologicals, Inc.
1 antibody
Rockland Immunochemicals, Inc.
1 antibody