ABIN499545

antibody from antibodies-online

Targeting: CASP10 FLICE-2, MCH4

Western blot (Supportive data in Antibodypedia)

ELISA (Recommended by provider)

Antibody Data

Product number

ABIN499545

Provider

antibodies-online

Product name

anti-Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10) (C-Term) antibody

Antibody type

Polyclonal

Antigen

Human Caspase-10 (C-Terminus) Peptide (AP30189CP-N)

Description

DEAE

Reactivity

Human

Host

Rabbit

Epitope

C-Term

Isotype

IgG

Vial size

0.1 mg

Storage

Store the antibody undiluted at 2-8°C.

References

Submitted references

Fas-associated death domain protein interleukin-1beta-converting enzyme 2 (FLICE2), an ICE/Ced-3 homologue, is proximally involved in CD95- and p55-mediated death signaling.

Vincenz C, Dixit VM
The Journal of biological chemistry 1997 Mar 7;272(10):6578-83

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Caspases: the executioners of apoptosis.

Cohen GM
The Biochemical journal 1997 Aug 15;326 ( Pt 1):1-16

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In vitro activation of CPP32 and Mch3 by Mch4, a novel human apoptotic cysteine protease containing two FADD-like domains.

Fernandes-Alnemri T, Armstrong RC, Krebs J, Srinivasula SM, Wang L, Bullrich F, Fritz LC, Trapani JA, Tomaselli KJ, Litwack G, Alnemri ES
Proceedings of the National Academy of Sciences of the United States of America 1996 Jul 23;93(15):7464-9

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Molecular cloning of YPT1/SEC4-related cDNAs from an epithelial cell line.

Chavrier P, Vingron M, Sander C, Simons K, Zerial M
Molecular and cellular biology 1990 Dec;10(12):6578-85

Western blot

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

Western blot analysis of caspase-10 in HeLa (H), Jurkat (J), A431 (A), K562 (K) whole cell lysates with AP30189PU-N Caspase-10 antibody at 1 ?g/ml.