Tissue expression
Cell line expression
Protein structure
USP5
Ubiquitin specific peptidase 5IsoT
Ubiquitin (see MIM 191339)-dependent proteolysis is a complex pathway of protein metabolism implicated in such diverse cellular functions as maintenance of chromatin structure, receptor function, and degradation of abnormal proteins. A late step of the process involves disassembly of the polyubiquitin chains on degraded proteins into ubiquitin monomers. USP5 disassembles branched polyubiquitin chains by a sequential exo mechanism, starting at the proximal end of the chain (Wilkinson et al., 1995 [PubMed 7578059]). [supplied by OMIM, Mar 2010]
Top validated antibodies |
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| Proteintech Group | 37 references | Polyclonal |
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| LSBio | Monoclonal |
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| Invitrogen Antibodies | Polyclonal |
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| Novus Biologicals | Polyclonal |
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| antibodies-online | Polyclonal |
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