PRSS16

This gene encodes a serine protease expressed exclusively in the thymus. It is thought to play a role in the alternative antigen presenting pathway used by cortical thymic epithelial cells during the positive selection of T cells. The gene is found in the large histone gene cluster on chromosome 6, near the major histocompatibility complex (MHC) class I region. A second transcript variant has been described, but its full length nature has not been determined. [provided by RefSeq, Jul 2008]

Description

Serine protease 16

Tissue specificity

Tissue enriched (lymphoid tissue)

Predicted location

Intracellular, Secreted in other tissues

Protein family

Enzymes
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Predicted secreted proteins

Chromosome

6 (27247701 - 27256624)

Ensembl ID

ENSG00000112812  (ver. 103.38)

Orthologs

Mouse Prss16: ENSMUSG00000006179

UniProt

Q9NQE7

neXtProt

NX_Q9NQE7

Human splice variants
Mouse splice variants

Protein structure