USP20

gene product
KIAA1003
This gene encodes a ubiquitin specific processing protease that was first identified as a substrate of the VHL (von Hippel-Lindau disease) protein E3 ubiquitin ligase complex. In addition to being ubiquitinated by the VHL-E3 ligase complex, this enzyme deubiquitinates hypoxia-inducible factor (HIF)-1 alpha and thereby causes increased expression of HIF-1alpha targeted genes which play a role in angiogenesis, glucose metabolism, cell proliferation and metastasis. The enzyme encoded by this gene also regulates G-protein coupled receptor signaling by mediating the deubiquitination of beta-2 adrenergic receptor (ADRB2). This enzyme is a ubiquitously expressed thiolester hydrolase. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jan 2013]
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308 antibodies from 28 providers.

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Antibody
Novus Biologicals
7 antibodies
antibodies-online
115 antibodies
Atlas Antibodies
1 antibody
NovoPro Bioscience Inc.
1 antibody
Proteintech Group
1 antibody
Biorbyt
14 antibodies
Antibodies.com
1 antibody
LifeSpan BioSciences, Inc.
71 antibodies
Abnova Corporation
9 antibodies
Aviva Systems Biology
4 antibodies
GeneTex
2 antibodies
ProSci
5 antibodies
Bethyl Laboratories
1 antibody
St John's Laboratory
1 antibody
Invitrogen Antibodies
4 antibodies
Arigo
1 antibody
Everest Biotech
1 antibody
NSJ Bioreagents
1 antibody
OriGene
5 antibodies
Acris Antibodies GmbH
3 antibodies
Creative Diagnostics
4 antibodies
MyBioSource
9 antibodies
Creative Biolabs
2 antibodies
Sigma-Aldrich
7 antibodies
United States Biological
31 antibodies
RayBiotech, Inc.
3 antibodies
Abgent
2 antibodies
Exalpha Biologicals, Inc.
2 antibodies