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- References [15]
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- Immunohistochemistry [2]
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- Product number
- 17491-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#17491-1-AP, RRID:AB_2212570
- Product name
- USP20 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated USP20 antibody (Cat. #17491-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references A novel PDIA3/FTO/USP20 positive feedback regulatory loop induces osteogenic differentiation of preosteoblast in osteoporosis.
Autophagy dysregulation via the USP20-ULK1 axis in the HERC2-related neurodevelopmental disorder.
USP20 is a predictor of poor prognosis in colorectal cancer and associated with lymph node metastasis, immune infiltration and chemotherapy resistance.
Electroacupuncture regulates hepatic cholesterol synthesis by HMGCR deubiquitination in rats.
Targeting histone deacetylase suppresses tumor growth through eliciting METTL14-modified m(6) A RNA methylation in ocular melanoma.
ATR-dependent ubiquitin-specific protease 20 phosphorylation confers oxaliplatin and ferroptosis resistance.
Oncogenic KRAS effector USP13 promotes metastasis in non-small cell lung cancer through deubiquitinating β-catenin.
Sleeve gastrectomy improves lipid dysmetabolism by downregulating the USP20-HSPA2 axis in diet-induced obese mice.
Hepatokine ERAP1 Disturbs Skeletal Muscle Insulin Sensitivity Via Inhibiting USP33-Mediated ADRB2 Deubiquitination.
The deubiquitinating enzyme USP20 regulates the stability of the MCL1 protein.
Deubiquitinases USP20/33 promote the biogenesis of tail-anchored membrane proteins.
USP18 and USP20 restrict oHSV-1 replication in resistant human oral squamous carcinoma cell line SCC9 and affect the viability of SCC9 cells.
Deubiquitinase USP20 promotes breast cancer metastasis by stabilizing SNAI2.
USP20 positively regulates tumorigenesis and chemoresistance through β-catenin stabilization.
Deubiquitinating enzyme USP20 is a positive regulator of Claspin and suppresses the malignant characteristics of gastric cancer cells.
Zhang F, Liu C, Chen Z, Zhao C
Cell biology international 2024 Apr;48(4):541-550
Cell biology international 2024 Apr;48(4):541-550
Autophagy dysregulation via the USP20-ULK1 axis in the HERC2-related neurodevelopmental disorder.
Sala-Gaston J, Pérez-Villegas EM, Armengol JA, Rawlins LE, Baple EL, Crosby AH, Ventura F, Rosa JL
Cell death discovery 2024 Apr 3;10(1):163
Cell death discovery 2024 Apr 3;10(1):163
USP20 is a predictor of poor prognosis in colorectal cancer and associated with lymph node metastasis, immune infiltration and chemotherapy resistance.
Jin R, Luo Z, Jun-Li, Tao Q, Wang P, Cai X, Jiang L, Zeng C, Chen Y
Frontiers in oncology 2023;13:1023292
Frontiers in oncology 2023;13:1023292
Electroacupuncture regulates hepatic cholesterol synthesis by HMGCR deubiquitination in rats.
Jin SW, Han YL, Pan XL, Zhang HX
Heliyon 2023 Oct;9(10):e21005
Heliyon 2023 Oct;9(10):e21005
Targeting histone deacetylase suppresses tumor growth through eliciting METTL14-modified m(6) A RNA methylation in ocular melanoma.
Zhuang A, Gu X, Ge T, Wang S, Ge S, Chai P, Jia R, Fan X
Cancer communications (London, England) 2023 Nov;43(11):1185-1206
Cancer communications (London, England) 2023 Nov;43(11):1185-1206
ATR-dependent ubiquitin-specific protease 20 phosphorylation confers oxaliplatin and ferroptosis resistance.
Tang J, Long G, Xiao D, Liu S, Xiao L, Zhou L, Tao Y
MedComm 2023 Dec;4(6):e463
MedComm 2023 Dec;4(6):e463
Oncogenic KRAS effector USP13 promotes metastasis in non-small cell lung cancer through deubiquitinating β-catenin.
Guo Y, Tian J, Guo Y, Wang C, Chen C, Cai S, Yu W, Sun B, Yan J, Li Z, Fan J, Qi Q, Zhang D, Jin W, Hua Z, Chen G
Cell reports 2023 Dec 26;42(12):113511
Cell reports 2023 Dec 26;42(12):113511
Sleeve gastrectomy improves lipid dysmetabolism by downregulating the USP20-HSPA2 axis in diet-induced obese mice.
Zhang W, Shi B, Li S, Liu Z, Li S, Dong S, Cheng Y, Zhu J, Zhang G, Zhong M
Frontiers in endocrinology 2022;13:1041027
Frontiers in endocrinology 2022;13:1041027
Hepatokine ERAP1 Disturbs Skeletal Muscle Insulin Sensitivity Via Inhibiting USP33-Mediated ADRB2 Deubiquitination.
Niu Y, Jiang H, Yin H, Wang F, Hu R, Hu X, Peng B, Shu Y, Li Z, Chen S, Guo F
Diabetes 2022 May 1;71(5):921-933
Diabetes 2022 May 1;71(5):921-933
The deubiquitinating enzyme USP20 regulates the stability of the MCL1 protein.
Feng J, Liu P, Li X, Zhang D, Lin H, Hou Z, Guo C, Niu Y, Dai B, Wang O, Qi M, Wang H, Zhou H
Biochemical and biophysical research communications 2022 Feb 19;593:122-128
Biochemical and biophysical research communications 2022 Feb 19;593:122-128
Deubiquitinases USP20/33 promote the biogenesis of tail-anchored membrane proteins.
Culver JA, Mariappan M
The Journal of cell biology 2021 May 3;220(5)
The Journal of cell biology 2021 May 3;220(5)
USP18 and USP20 restrict oHSV-1 replication in resistant human oral squamous carcinoma cell line SCC9 and affect the viability of SCC9 cells.
Lu R, Wu G, Chen M, Ji D, Liu Y, Zhou GG, Fu W
Molecular therapy oncolytics 2021 Dec 17;23:477-487
Molecular therapy oncolytics 2021 Dec 17;23:477-487
Deubiquitinase USP20 promotes breast cancer metastasis by stabilizing SNAI2.
Li W, Shen M, Jiang YZ, Zhang R, Zheng H, Wei Y, Shao ZM, Kang Y
Genes & development 2020 Oct 1;34(19-20):1310-1315
Genes & development 2020 Oct 1;34(19-20):1310-1315
USP20 positively regulates tumorigenesis and chemoresistance through β-catenin stabilization.
Wu C, Luo K, Zhao F, Yin P, Song Y, Deng M, Huang J, Chen Y, Li L, Lee S, Kim J, Zhou Q, Tu X, Nowsheen S, Luo Q, Gao X, Lou Z, Liu Z, Yuan J
Cell death and differentiation 2018 Nov;25(10):1855-1869
Cell death and differentiation 2018 Nov;25(10):1855-1869
Deubiquitinating enzyme USP20 is a positive regulator of Claspin and suppresses the malignant characteristics of gastric cancer cells.
Wang C, Yang C, Ji J, Jiang J, Shi M, Cai Q, Yu Y, Zhu Z, Zhang J
International journal of oncology 2017 Apr;50(4):1136-1146
International journal of oncology 2017 Apr;50(4):1136-1146
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HepG2 cells were subjected to SDS PAGE followed by western blot with 17491-1-AP(USP20 antibody) at dilution of 1:400
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human kidney using 17491-1-AP(USP20 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The USP20 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human USP20. This antibody recognizes human,mouse,rat antigen. The USP20 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
