MBTPS1

gene product
KIAA0091, PCSK8, S1P, SKI-1
This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to the cis/medial-Golgi where a second autocatalytic event takes place and the catalytic activity is acquired. It encodes a type 1 membrane bound protease which is ubiquitously expressed and regulates cholesterol or lipid homeostasis via cleavage of substrates at non-basic residues. Mutations in this gene may be associated with lysosomal dysfunction. [provided by RefSeq, Feb 2014]
More gene data

Featured antibodies

Antibodies

 

Filters

Antibodypedia Validation Initiative

Validation method

Application

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

  or   Clear
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Validated within AVI
Eligible for validation within AVI
69 antibodies from 20 providers.

Antibody properties

Applications

or Cancel
AntibodyRefsTypeAVIWBELICCIPIHCFC
GeneTex
2 antibodies
Biorbyt
9 antibodies
LifeSpan BioSciences, Inc.
19 antibodies
Bioworld Technology, Inc
1 antibody
Invitrogen Antibodies
3 antibodies
Novus Biologicals
2 antibodies
Abnova Corporation
2 antibodies
Affinity Biosciences
1 antibody
antibodies-online
11 antibodies
Aviva Systems Biology
1 antibody
Atlas Antibodies
1 antibody
OriGene
1 antibody
St John's Laboratory
3 antibodies
Creative Diagnostics
4 antibodies
Boster Biological Technology
1 antibody
MyBioSource
1 antibody
NovoPro Bioscience Inc.
1 antibody
Sigma-Aldrich
2 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Creative Biolabs
3 antibodies