Antibody data
- Antibody Data
- Antigen structure
- References [13]
- Comments [0]
- Validations
- Western blot [1]
- Immunoprecipitation [2]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 10221-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10221-1-AP, RRID:AB_2161789
- Product name
- PDLIM7 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated PDLIM7 antibody (Cat. #10221-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references TPM2 attenuates progression of prostate cancer by blocking PDLIM7-mediated nuclear translocation of YAP1.
Regulatory and Interacting Partners of PDLIM7 in Thyroid Cancer.
LIM Mineralization Protein-1 Enhances the Committed Differentiation of Dental Pulp Stem Cells through the ERK1/2 and p38 MAPK Pathways and BMP Signaling.
Proteomic identification and structural basis for the interaction between sorting nexin SNX17 and PDLIM family proteins.
PDLIM7 Synergizes With PDLIM2 and p62/Sqstm1 to Inhibit Inflammatory Signaling by Promoting Degradation of the p65 Subunit of NF-κB.
Physical and Molecular Landscapes of Mouse Glioma Extracellular Vesicles Define Heterogeneity.
Salt-inducible kinase induces cytoplasmic histone deacetylase 4 to promote vascular calcification.
Proteomic profiling of human placenta-derived mesenchymal stem cells upon transforming LIM mineralization protein-1 stimulation.
LIM mineralization protein-1 suppresses TNF-α induced intervertebral disc degeneration by maintaining nucleus pulposus extracellular matrix production and inhibiting matrix metalloproteinases expression.
LIM Mineralization Protein-1 Enhances Bone Morphogenetic Protein-2-Mediated Osteogenesis Through Activation of ERK1/2 MAPK Pathway and Upregulation of Runx2 Transactivity.
LIM mineralization protein-1 inhibits the malignant phenotypes of human osteosarcoma cells.
Immunohistochemical localization of LIM mineralization protein 1 during mouse molar development.
Immunohistochemical localization of LIM mineralization protein 1 in pulp-dentin complex of human teeth with normal and pathologic conditions.
Wu Z, Ge L, Ma L, Lu M, Song Y, Deng S, Duan P, Du T, Wu Y, Zhang Z, Zhang S
Cell & bioscience 2023 Feb 23;13(1):39
Cell & bioscience 2023 Feb 23;13(1):39
Regulatory and Interacting Partners of PDLIM7 in Thyroid Cancer.
Rood K, Yamauchi CR, Sharma U, Laxa RT, Robins C, Lanza G, Sánchez-Ruiz K, Khan A, Kim HS, Shields A, Kennedy K, Mirshahidi S, Perez MC, Firek A, Munir I, Simental AA, Khan S
Current oncology (Toronto, Ont.) 2023 Dec 13;30(12):10450-10462
Current oncology (Toronto, Ont.) 2023 Dec 13;30(12):10450-10462
LIM Mineralization Protein-1 Enhances the Committed Differentiation of Dental Pulp Stem Cells through the ERK1/2 and p38 MAPK Pathways and BMP Signaling.
Mu R, Chen B, Bi B, Yu H, Liu J, Li J, He M, Rong L, Liu B, Liu K, Zhu L, Shi X, Shuai Y, Jin L
International journal of medical sciences 2022;19(8):1307-1319
International journal of medical sciences 2022;19(8):1307-1319
Proteomic identification and structural basis for the interaction between sorting nexin SNX17 and PDLIM family proteins.
Healy MD, Sacharz J, McNally KE, McConville C, Tillu VA, Hall RJ, Chilton M, Cullen PJ, Mobli M, Ghai R, Stroud DA, Collins BM
Structure (London, England : 1993) 2022 Dec 1;30(12):1590-1602.e6
Structure (London, England : 1993) 2022 Dec 1;30(12):1590-1602.e6
PDLIM7 Synergizes With PDLIM2 and p62/Sqstm1 to Inhibit Inflammatory Signaling by Promoting Degradation of the p65 Subunit of NF-κB.
Jodo A, Shibazaki A, Onuma A, Kaisho T, Tanaka T
Frontiers in immunology 2020;11:1559
Frontiers in immunology 2020;11:1559
Physical and Molecular Landscapes of Mouse Glioma Extracellular Vesicles Define Heterogeneity.
Gyuris A, Navarrete-Perea J, Jo A, Cristea S, Zhou S, Fraser K, Wei Z, Krichevsky AM, Weissleder R, Lee H, Gygi SP, Charest A
Cell reports 2019 Jun 25;27(13):3972-3987.e6
Cell reports 2019 Jun 25;27(13):3972-3987.e6
Salt-inducible kinase induces cytoplasmic histone deacetylase 4 to promote vascular calcification.
Abend A, Shkedi O, Fertouk M, Caspi LH, Kehat I
EMBO reports 2017 Jul;18(7):1166-1185
EMBO reports 2017 Jul;18(7):1166-1185
Proteomic profiling of human placenta-derived mesenchymal stem cells upon transforming LIM mineralization protein-1 stimulation.
Zhu Z, Liu Z, Liu J, Bi M, Yang T, Wang J
Cytotechnology 2015 Mar;67(2):285-97
Cytotechnology 2015 Mar;67(2):285-97
LIM mineralization protein-1 suppresses TNF-α induced intervertebral disc degeneration by maintaining nucleus pulposus extracellular matrix production and inhibiting matrix metalloproteinases expression.
Liu H, Pan H, Yang H, Wang J, Zhang K, Li X, Wang H, Ding W, Li B, Zheng Z
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2015 Mar;33(3):294-303
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2015 Mar;33(3):294-303
LIM Mineralization Protein-1 Enhances Bone Morphogenetic Protein-2-Mediated Osteogenesis Through Activation of ERK1/2 MAPK Pathway and Upregulation of Runx2 Transactivity.
Pan H, Li X, Wang J, Zhang K, Yang H, Li Z, Zheng Z, Liu H
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2015 Aug;30(8):1523-35
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2015 Aug;30(8):1523-35
LIM mineralization protein-1 inhibits the malignant phenotypes of human osteosarcoma cells.
Liu H, Huang L, Zhang Z, Zhang Z, Yu Z, Chen X, Chen Z, Zen Y, Yang D, Han Z, Shu Y, Dai M, Cao K
International journal of molecular sciences 2014 Apr 23;15(4):7037-48
International journal of molecular sciences 2014 Apr 23;15(4):7037-48
Immunohistochemical localization of LIM mineralization protein 1 during mouse molar development.
Fang P, Wang X, Zhang L, Yuan G, Chen Z, Zhang Q
Journal of molecular histology 2010 Oct;41(4-5):199-203
Journal of molecular histology 2010 Oct;41(4-5):199-203
Immunohistochemical localization of LIM mineralization protein 1 in pulp-dentin complex of human teeth with normal and pathologic conditions.
Wang X, Zhang Q, Chen Z, Zhang L
Journal of endodontics 2008 Feb;34(2):143-7
Journal of endodontics 2008 Feb;34(2):143-7
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- SKOV-3 cells were subjected to SDS PAGE followed by western blot with 10221-1-AP(PDLIM7,LMP1 antibody) at dilution of 1:2000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-PDLIM7,LMP1 (IP:10221-1-AP, 3ug; Detection:10221-1-AP 1:1000) with HeLa cells lysate 4650ug.
- Sample type
- cell line
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP result of PDLIM7 antibody (10221-1-AP for IP and Detection) with HeLa cell lysate.
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The PDLIM7 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human PDLIM7. This antibody recognizes human,mouse,rat antigen. The PDLIM7 antibody has been validated for the following applications: ELISA, WB, IP, IHC analysis.