Tissue expression
Cell line expression
Protein structure
PDLIM7
PDZ and LIM domain 7ENIGMA
The protein encoded by this gene is representative of a family of proteins composed of conserved PDZ and LIM domains. LIM domains are proposed to function in protein-protein recognition in a variety of contexts including gene transcription and development and in cytoskeletal interaction. The LIM domains of this protein bind to protein kinases, whereas the PDZ domain binds to actin filaments. The gene product is involved in the assembly of an actin filament-associated complex essential for transmission of ret/ptc2 mitogenic signaling. The biological function is likely to be that of an adapter, with the PDZ domain localizing the LIM-binding proteins to actin filaments of both skeletal muscle and nonmuscle tissues. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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Proteintech Group | 10221-1-AP | 13 references | Polyclonal |
WB
EL
ICC
IP
IHC
|
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Novus Biologicals | H00009260-M01 | 1 references | Monoclonal |
WB
EL
ICC
IP
BN
|
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Abnova Corporation | H00009260-M01 | 1 references | Monoclonal |
WB
EL
ICC
IP |
|
Invitrogen Antibodies | 10221-1-AP | Polyclonal |
WB
ICC
IP
IHC
OA
|
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antibodies-online | ABIN563997 | 1 references | Monoclonal |
WB
EL
ICC
IP |
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Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider