DMAB12154

antibody from Creative Diagnostics

Targeting: PDLIM7 ENIGMA

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

DMAB12154

Provider

Creative Diagnostics

Proper citation

Creative Diagnostics Cat#DMAB12154, RRID:AB_2431087

Product name

Anti-LMP monoclonal antibody, clone Njyfe

Antibody type

Monoclonal

Description

EBV is a human herpesvirus that establishes a life-long persistence in the host. The virus infects the vast majority of the world"s adult population and is well known for its association with a broad spectrum of benign and malignant diseases, including infectious mononucleosis, Burkitt"s lymphoma, nasopharyngeal carcinoma, and is causally associated with lymphoid and epithelial malignancies, including post-transplant lymphoproliferative disorders, Hodgkin"s disease, anaplastic nasopharyngeal carcinoma and gastric carcinomas. Latent membrane protein2(LMP1) of Epstein-Barr virus (EBV) is a transforming protein that affects multiple cell signalling pathways and contributes to EBV-associated oncogenesis. LMP1 can be expressed in some states of EBV latency, and significant induction of full-length LMP1 is also observed frequently during virus reactivation into the lytic cycle. LMP1 is critical for EBV-infected cell activation, adhesion and survival, and is usually expressed in the malignant cells.

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

Njyfe

Vial size

1 ea

Storage

Store at 4°C on dry atmosphere.After reconstitution with distilled water, store at -20°C.Aliquot to avoid repeated freezing and thawing.