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- References [7]
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- Product number
- NBP2-24904 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Rabbit Polyclonal TLR3 Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.02 mg
- Concentration
- 1.0 mg/ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Submitted references Interferon β (IFN-β) Production during the Double-stranded RNA (dsRNA) Response in Hepatocytes Involves Coordinated and Feedforward Signaling through Toll-like Receptor 3 (TLR3), RNA-dependent Protein Kinase (PKR), Inducible Nitric Oxide Synthase (iNOS), and Src Protein.
Novel Types of Small RNA Exhibit Sequence- and Target-dependent Angiogenesis Suppression Without Activation of Toll-like Receptor 3 in an Age-related Macular Degeneration (AMD) Mouse Model.
Inhibition of choroidal fibrovascular membrane formation by new class of RNA interference therapeutic agent targeting periostin.
The inducible nitric-oxide synthase (iNOS)/Src axis mediates Toll-like receptor 3 tyrosine 759 phosphorylation and enhances its signal transduction, leading to interferon-β synthesis in macrophages.
Short-interfering RNAs induce retinal degeneration via TLR3 and IRF3.
Small interfering RNA-induced TLR3 activation inhibits blood and lymphatic vessel growth.
Viral double-stranded RNA triggers Ig class switching by activating upper respiratory mucosa B cells through an innate TLR3 pathway involving BAFF.
Zhang L, Xiang W, Wang G, Yan Z, Zhu Z, Guo Z, Sengupta R, Chen AF, Loughran PA, Lu B, Wang Q, Billiar TR
The Journal of biological chemistry 2016 Jul 15;291(29):15093-107
The Journal of biological chemistry 2016 Jul 15;291(29):15093-107
Novel Types of Small RNA Exhibit Sequence- and Target-dependent Angiogenesis Suppression Without Activation of Toll-like Receptor 3 in an Age-related Macular Degeneration (AMD) Mouse Model.
Takanashi M, Sudo K, Ueda S, Ohno S, Yamada Y, Osakabe Y, Goto H, Matsunaga Y, Ishikawa A, Usui Y, Kuroda M
Molecular therapy. Nucleic acids 2015 Oct 20;4:e258
Molecular therapy. Nucleic acids 2015 Oct 20;4:e258
Inhibition of choroidal fibrovascular membrane formation by new class of RNA interference therapeutic agent targeting periostin.
Nakama T, Yoshida S, Ishikawa K, Kobayashi Y, Zhou Y, Nakao S, Sassa Y, Oshima Y, Takao K, Shimahara A, Yoshikawa K, Hamasaki T, Ohgi T, Hayashi H, Matsuda A, Kudo A, Nozaki M, Ogura Y, Kuroda M, Ishibashi T
Gene therapy 2015 Feb;22(2):127-37
Gene therapy 2015 Feb;22(2):127-37
The inducible nitric-oxide synthase (iNOS)/Src axis mediates Toll-like receptor 3 tyrosine 759 phosphorylation and enhances its signal transduction, leading to interferon-β synthesis in macrophages.
Hsieh MY, Chang MY, Chen YJ, Li YK, Chuang TH, Yu GY, Cheung CH, Chen HC, Maa MC, Leu TH
The Journal of biological chemistry 2014 Mar 28;289(13):9208-20
The Journal of biological chemistry 2014 Mar 28;289(13):9208-20
Short-interfering RNAs induce retinal degeneration via TLR3 and IRF3.
Kleinman ME, Kaneko H, Cho WG, Dridi S, Fowler BJ, Blandford AD, Albuquerque RJ, Hirano Y, Terasaki H, Kondo M, Fujita T, Ambati BK, Tarallo V, Gelfand BD, Bogdanovich S, Baffi JZ, Ambati J
Molecular therapy : the journal of the American Society of Gene Therapy 2012 Jan;20(1):101-8
Molecular therapy : the journal of the American Society of Gene Therapy 2012 Jan;20(1):101-8
Small interfering RNA-induced TLR3 activation inhibits blood and lymphatic vessel growth.
Cho WG, Albuquerque RJ, Kleinman ME, Tarallo V, Greco A, Nozaki M, Green MG, Baffi JZ, Ambati BK, De Falco M, Alexander JS, Brunetti A, De Falco S, Ambati J
Proceedings of the National Academy of Sciences of the United States of America 2009 Apr 28;106(17):7137-42
Proceedings of the National Academy of Sciences of the United States of America 2009 Apr 28;106(17):7137-42
Viral double-stranded RNA triggers Ig class switching by activating upper respiratory mucosa B cells through an innate TLR3 pathway involving BAFF.
Xu W, Santini PA, Matthews AJ, Chiu A, Plebani A, He B, Chen K, Cerutti A
Journal of immunology (Baltimore, Md. : 1950) 2008 Jul 1;181(1):276-87
Journal of immunology (Baltimore, Md. : 1950) 2008 Jul 1;181(1):276-87
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- Western Blot: TLR3 [p Tyr759] Antibody [NBP2-24904] - Image from verified customer review.
