TLR3

gene product
CD283
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor is most abundantly expressed in placenta and pancreas, and is restricted to the dendritic subpopulation of the leukocytes. It recognizes dsRNA associated with viral infection, and induces the activation of NF-kappaB and the production of type I interferons. It may thus play a role in host defense against viruses. Use of alternative polyadenylation sites to generate different length transcripts has been noted for this gene. [provided by RefSeq, Jul 2008]
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1136 antibodies from 46 providers.

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Antibody
Novus Biologicals
99 antibodies
antibodies-online
328 antibodies
Enzo Life Sciences
7 antibodies
GeneTex
9 antibodies
Abnova Corporation
10 antibodies
Invitrogen Antibodies
28 antibodies
OriGene
24 antibodies
Proteintech Group
1 antibody
Acris Antibodies GmbH
33 antibodies
LifeSpan BioSciences, Inc.
232 antibodies
NovoPro Bioscience Inc.
9 antibodies
Biorbyt
37 antibodies
BioLegend
7 antibodies
Arigo
2 antibodies
Rockland Immunochemicals, Inc.
4 antibodies
R&D Systems
7 antibodies
Boster Biological Technology
3 antibodies
ProSci
5 antibodies
Affinity Biosciences
2 antibodies
Abgent
9 antibodies
NSJ Bioreagents
6 antibodies
Aviva Systems Biology
8 antibodies
Bioworld Technology, Inc
1 antibody
FabGennix
3 antibodies
Creative Biolabs
75 antibodies
BioLegend (formerly Covance Antibody Products)
1 antibody
ABEOMICS Inc.
5 antibodies
Creative Diagnostics
9 antibodies
Miltenyi Biotec
15 antibodies
MyBioSource
17 antibodies
Abbexa
16 antibodies
Leading Biology
9 antibodies
St John's Laboratory
3 antibodies
GenWay
9 antibodies
RayBiotech, Inc.
5 antibodies
Abbiotec
2 antibodies
Abiocode, Inc.
2 antibodies
United States Biological
64 antibodies
Active Motif
1 antibody
Cell Signaling Technology, Inc
1 antibody
RabMAbs
1 antibody
eBioscience, An Affymetrix Company
6 antibodies
Sigma-Aldrich
4 antibodies
EMD Millipore
3 antibodies
Exalpha Biologicals, Inc.
2 antibodies