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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [14]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
- Flow cytometry [2]
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- Product number
- NB100-56571 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB100-56571, RRID:AB_2204880
- Product name
- Rabbit Polyclonal TLR3 Antibody
- Antibody type
- Polyclonal
- Description
- Protein G purified.
- Reactivity
- Human, Mouse, Porcine
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 mg
- Concentration
- 1.0 mg/ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Submitted references TLR3 contributes to persistent autophagy and heart failure in mice after myocardial infarction.
Pellino-1 confers chemoresistance in lung cancer cells by upregulating cIAP2 through Lys63-mediated polyubiquitination.
MicroRNA-155 controls Toll-like receptor 3- and hepatitis C virus-induced immune responses in the liver.
Differential regulation of TLR mediated innate immune response of mouse neuronal cells following infection with novel ECSA genotype of Chikungunya virus with and without E1:A226V mutation.
Epidermal growth factor receptor is essential for Toll-like receptor 3 signaling.
Short-interfering RNAs induce retinal degeneration via TLR3 and IRF3.
Differential, type I interferon-mediated autophagic trafficking of hepatitis C virus proteins in mouse liver.
Toll-like receptor-induced innate immune responses in non-parenchymal liver cells are cell type-specific.
Small interfering RNA-induced TLR3 activation inhibits blood and lymphatic vessel growth.
Sequence- and target-independent angiogenesis suppression by siRNA via TLR3.
Expression and regulation of Toll-like receptors in lupus-like immune complex glomerulonephritis of MRL-Fas(lpr) mice.
Toll-like receptor-7 modulates immune complex glomerulonephritis.
Ligands to nucleic acid-specific toll-like receptors and the onset of lupus nephritis.
Viral double-stranded RNA aggravates lupus nephritis through Toll-like receptor 3 on glomerular mesangial cells and antigen-presenting cells.
Gao T, Zhang SP, Wang JF, Liu L, Wang Y, Cao ZY, Hu QK, Yuan WJ, Lin L
Journal of cellular and molecular medicine 2018 Jan;22(1):395-408
Journal of cellular and molecular medicine 2018 Jan;22(1):395-408
Pellino-1 confers chemoresistance in lung cancer cells by upregulating cIAP2 through Lys63-mediated polyubiquitination.
Jeon YK, Kim CK, Koh J, Chung DH, Ha GH
Oncotarget 2016 Jul 5;7(27):41811-41824
Oncotarget 2016 Jul 5;7(27):41811-41824
MicroRNA-155 controls Toll-like receptor 3- and hepatitis C virus-induced immune responses in the liver.
Jiang M, Broering R, Trippler M, Wu J, Zhang E, Zhang X, Gerken G, Lu M, Schlaak JF
Journal of viral hepatitis 2014 Feb;21(2):99-110
Journal of viral hepatitis 2014 Feb;21(2):99-110
Differential regulation of TLR mediated innate immune response of mouse neuronal cells following infection with novel ECSA genotype of Chikungunya virus with and without E1:A226V mutation.
Priya R, Dhanwani R, Patro IK, Rao PV, Parida MM
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 2013 Dec;20:396-406
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 2013 Dec;20:396-406
Epidermal growth factor receptor is essential for Toll-like receptor 3 signaling.
Yamashita M, Chattopadhyay S, Fensterl V, Saikia P, Wetzel JL, Sen GC
Science signaling 2012 Jul 17;5(233):ra50
Science signaling 2012 Jul 17;5(233):ra50
Short-interfering RNAs induce retinal degeneration via TLR3 and IRF3.
Kleinman ME, Kaneko H, Cho WG, Dridi S, Fowler BJ, Blandford AD, Albuquerque RJ, Hirano Y, Terasaki H, Kondo M, Fujita T, Ambati BK, Tarallo V, Gelfand BD, Bogdanovich S, Baffi JZ, Ambati J
Molecular therapy : the journal of the American Society of Gene Therapy 2012 Jan;20(1):101-8
Molecular therapy : the journal of the American Society of Gene Therapy 2012 Jan;20(1):101-8
Differential, type I interferon-mediated autophagic trafficking of hepatitis C virus proteins in mouse liver.
Desai MM, Gong B, Chan T, Davey RA, Soong L, Kolokoltsov AA, Sun J
Gastroenterology 2011 Aug;141(2):674-85, 685.e1-6
Gastroenterology 2011 Aug;141(2):674-85, 685.e1-6
Toll-like receptor-induced innate immune responses in non-parenchymal liver cells are cell type-specific.
Wu J, Meng Z, Jiang M, Zhang E, Trippler M, Broering R, Bucchi A, Krux F, Dittmer U, Yang D, Roggendorf M, Gerken G, Lu M, Schlaak JF
Immunology 2010 Mar;129(3):363-74
Immunology 2010 Mar;129(3):363-74
Small interfering RNA-induced TLR3 activation inhibits blood and lymphatic vessel growth.
Cho WG, Albuquerque RJ, Kleinman ME, Tarallo V, Greco A, Nozaki M, Green MG, Baffi JZ, Ambati BK, De Falco M, Alexander JS, Brunetti A, De Falco S, Ambati J
Proceedings of the National Academy of Sciences of the United States of America 2009 Apr 28;106(17):7137-42
Proceedings of the National Academy of Sciences of the United States of America 2009 Apr 28;106(17):7137-42
Sequence- and target-independent angiogenesis suppression by siRNA via TLR3.
Kleinman ME, Yamada K, Takeda A, Chandrasekaran V, Nozaki M, Baffi JZ, Albuquerque RJ, Yamasaki S, Itaya M, Pan Y, Appukuttan B, Gibbs D, Yang Z, Karikó K, Ambati BK, Wilgus TA, DiPietro LA, Sakurai E, Zhang K, Smith JR, Taylor EW, Ambati J
Nature 2008 Apr 3;452(7187):591-7
Nature 2008 Apr 3;452(7187):591-7
Expression and regulation of Toll-like receptors in lupus-like immune complex glomerulonephritis of MRL-Fas(lpr) mice.
Patole PS, Pawar RD, Lech M, Zecher D, Schmidt H, Segerer S, Ellwart A, Henger A, Kretzler M, Anders HJ
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2006 Nov;21(11):3062-73
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2006 Nov;21(11):3062-73
Toll-like receptor-7 modulates immune complex glomerulonephritis.
Pawar RD, Patole PS, Zecher D, Segerer S, Kretzler M, Schlöndorff D, Anders HJ
Journal of the American Society of Nephrology : JASN 2006 Jan;17(1):141-9
Journal of the American Society of Nephrology : JASN 2006 Jan;17(1):141-9
Ligands to nucleic acid-specific toll-like receptors and the onset of lupus nephritis.
Pawar RD, Patole PS, Ellwart A, Lech M, Segerer S, Schlondorff D, Anders HJ
Journal of the American Society of Nephrology : JASN 2006 Dec;17(12):3365-73
Journal of the American Society of Nephrology : JASN 2006 Dec;17(12):3365-73
Viral double-stranded RNA aggravates lupus nephritis through Toll-like receptor 3 on glomerular mesangial cells and antigen-presenting cells.
Patole PS, Gröne HJ, Segerer S, Ciubar R, Belemezova E, Henger A, Kretzler M, Schlöndorff D, Anders HJ
Journal of the American Society of Nephrology : JASN 2005 May;16(5):1326-38
Journal of the American Society of Nephrology : JASN 2005 May;16(5):1326-38
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: TLR3 Antibody [NB100-56571] - Analysis of TLR3 in mouse spleen tissue lysate using NB100-56571 at 2 ug/ml.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry: TLR3 Antibody [NB100-56571] - Pig lung poisoned through aspiration with gastric juice and organophosphate (dimethoate EC40) after 48 hours of IC ventilation. Image from verified customer review.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Frozen: TLR3 Antibody [NB100-56571] - Frozen mouse eye tissue sections stained with TLR3, a retinal pigment epithelium (RPE) marker and DAPI. Top panel: TLR3 (red) colocalized with the RPE (green) marker. Bottom panel: Tissue stained with isotype control (no TLR3 Ab), RPE and DAPI. Data courtesy of Kleinman et al.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Flow Cytometry: TLR3 Antibody [NB100-56571] - Intracellular flow analysis of TLR3 in Balb/c mouse splenocytes and mouse RAW cells using TLR3 antibody (red) and isotype control antibody (green) at 1 ug/10^6 cells.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Flow Cytometry: TLR3 Antibody [NB100-56571] - Analysis using the FITC conjugate of NB100-56571. Staining of TLR3 in Balb/c mouse splenocytes using this antibody at 1 ug/10^6 cells. Green represents rabbit IgG isotype control this antibody; red represents anti-TLR3 antibody.
