RA0238

antibody from Oursmab

Targeting: F11 FXI

Western blot (Supportive data in Antibodypedia)

ELISA (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Functional assay (Recommended by provider)

Antibody Data

Product number

RA0238

Provider

Oursmab

Product name

Gruticibart (Biosimilar Reference Antibody) (F11)

Antibody type

Monoclonal

Description

Gruticibart (development code AB023) is an investigational, recombinant monoclonal antibody designed as a novel anticoagulant. It functions as a specific inhibitor of factor XI (FXI), a key component of the contact activation pathway of the coagulation system. By binding with high affinity to FXI, gruticibart prevents its activation to FXIa and thereby inhibits the downstream amplification of the coagulation cascade.

Reactivity

Human

Isotype

IgG

Vial size

100 ¦Ìg,1 mg,5 mg,10 mg,25 mg,50 mg,100 mg

Concentration

Bottled at the concentration indicated on the vial.

Storage

Store at -20¡ãC or -80¡ãC. Avoid repeated freeze.

Western blot

Supportive validation

Submitted by

Oursmab (provider)

Main image

Experimental details

Gruticibart (Biosimilar Reference Antibody) (F11)-RA0238-Oursmab determined by SDS-PAGE. The purity of the protein is greater than 98%.