Tissue expression
Cell line expression
Protein structure

F11

Coagulation factor XI
FXI 
This gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen, which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI, an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains, resulting in activated factor XIa, a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome, a blood coagulation abnormality. [provided by RefSeq, Jul 2008]
More gene data

All Antibodies

 

Filters

Application

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

Antigen sequence

Epitope

Antibody

  or   Clear
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
613 antibodies from 34 providers.

Antibody properties

Applications

or Cancel
AntibodyRefsTypeWBELICCIPIHCFC
Invitrogen Antibodies
16 antibodies
antibodies-online
128 antibodies
GeneTex
4 antibodies
Biorbyt
46 antibodies
Novus Biologicals
32 antibodies
Abnova Corporation
10 antibodies
R&D Systems
4 antibodies
OriGene
5 antibodies
Aviva Systems Biology
4 antibodies
Acris Antibodies GmbH
3 antibodies
Abgent
2 antibodies
Signalway Antibody LLC
1 antibody
Cusabio Biotech Co., Ltd
4 antibodies
Affinity Biosciences
1 antibody
Molecular Innovations
4 antibodies
Bioworld Technology, Inc
2 antibodies
Creative Biolabs
160 antibodies
Atlas Antibodies
1 antibody
ProSci
1 antibody
St John's Laboratory
1 antibody
MyBioSource
9 antibodies
Creative Diagnostics
7 antibodies
GenWay
3 antibodies
Abbexa
8 antibodies
Proteintech Group
1 antibody
RabMAbs
1 antibody
United States Biological
26 antibodies
Leading Biology
3 antibodies
Green Mountain Antibodies
1 antibody
Sino Biological Inc.
4 antibodies
MilliporeSigma / Merck KGaA
2 antibodies
Exalpha Biologicals, Inc.
1 antibody