ABIN358367

antibody from antibodies-online

Targeting: NFATC2 NF-ATP, NFAT1, NFATp

No application information provided.

Antibody Data

Product number

ABIN358367

Provider

antibodies-online

Product name

anti-Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 2 (NFAT1) (pSer330) antibody

Antibody type

Polyclonal

Description

Protein A Affinity Chromatography. Then, the antibody fraction is peptide affinity purified in a 2-step procedure with peptides. The antibody is eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Reactivity

Human

Host

Rabbit

Epitope

pSer330

Vial size

0.4 mL

Storage

Store the antibody undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.

Handling

Avoid repeated freezing and thawing.

References

Submitted references

Induction of the CTLA-4 gene in human lymphocytes is dependent on NFAT binding the proximal promoter.

Gibson HM, Hedgcock CJ, Aufiero BM, Wilson AJ, Hafner MS, Tsokos GC, Wong HK
Journal of immunology (Baltimore, Md. : 1950) 2007 Sep 15;179(6):3831-40

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Requirement for O-linked N-acetylglucosaminyltransferase in lymphocytes activation.

Golks A, Tran TT, Goetschy JF, Guerini D
The EMBO journal 2007 Oct 17;26(20):4368-79

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Structure-function analysis of the WIP role in T cell receptor-stimulated NFAT activation: evidence that WIP-WASP dissociation is not required and that the WIP NH2 terminus is inhibitory.

Dong X, Patino-Lopez G, Candotti F, Shaw S
The Journal of biological chemistry 2007 Oct 12;282(41):30303-10