Tissue expression
Cell line expression
Protein structure
TAF6
TATA-box binding protein associated factor 6MGC:8964, TAF2E, TAFII70, TAFII80, TAFII85
Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes one of the smaller subunits of TFIID that binds weakly to TBP but strongly to TAF1, the largest subunit of TFIID. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]
Top validated antibodies |
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Atlas Antibodies | HPA006566 | Polyclonal |
WB
ICC
IHC
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Biorbyt | orb313350 | Polyclonal |
WB
EL
ICC
IHC |
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Invitrogen Antibodies | PA5-52310 | Polyclonal |
WB
ICC
IHC
|
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Novus Biologicals | NB100-60640 | Polyclonal |
WB
IP
IHC
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antibodies-online | ABIN253111 | Polyclonal |
WB
ICC
IP
IHC |
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