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- Immunohistochemistry [1]
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- Product number
- ABIN400811 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Apoptotic Peptidase Activating Factor 1 (APAF1) (C-Term) antibody
- Antibody type
- Monoclonal
- Antigen
- Synthetic peptide corresponding to a region near the carboxy terminus of human Apaf1protein
- Description
- Affinity Chromatography on Protein A
- Reactivity
- Human, Mouse, Rat
- Host
- Mouse
- Epitope
- C-Term
- Isotype
- IgG
- Antibody clone number
- 2E10
- Vial size
- 0.1 mg
- Concentration
- 1.0 mg/mL (by UV absorbance at 280 nm)
- Storage
- Store the antibody at -20°C. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Submitted references Apaf1 (CED-4 homolog) regulates programmed cell death in mammalian development.
Bcl-XL interacts with Apaf-1 and inhibits Apaf-1-dependent caspase-9 activation.
Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade.
Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3.
Cecconi F, Alvarez-Bolado G, Meyer BI, Roth KA, Gruss P
Cell 1998 Sep 18;94(6):727-37
Cell 1998 Sep 18;94(6):727-37
Bcl-XL interacts with Apaf-1 and inhibits Apaf-1-dependent caspase-9 activation.
Hu Y, Benedict MA, Wu D, Inohara N, Núñez G
Proceedings of the National Academy of Sciences of the United States of America 1998 Apr 14;95(8):4386-91
Proceedings of the National Academy of Sciences of the United States of America 1998 Apr 14;95(8):4386-91
Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade.
Li P, Nijhawan D, Budihardjo I, Srinivasula SM, Ahmad M, Alnemri ES, Wang X
Cell 1997 Nov 14;91(4):479-89
Cell 1997 Nov 14;91(4):479-89
Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3.
Zou H, Henzel WJ, Liu X, Lutschg A, Wang X
Cell 1997 Aug 8;90(3):405-13
Cell 1997 Aug 8;90(3):405-13
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Supportive validation
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- antibodies-online (provider)
- Main image
- Experimental details
- Image(s): Western Blotting
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Image(s): Immunohistochemistry
