AMP00009G

antibody from Leading Biology

Targeting: IL1R2 CD121b, IL1RB

Flow cytometry (Recommended by provider)

Antibody Data

Product number

AMP00009G

Provider

Leading Biology

Product name

Functional IL-1R2 (mouse) Antibody, mAb (recombinant)

Antibody type

Monoclonal

Description

The inflammatory actions of IL-1α and -β- depend on their interaction with its receptor, IL-1R1, and can be negatively controlled by several inhibitors such as IL-1Ra, IL-1R type 2 (IL-1R2), SIGIRR and the soluble form of IL-1 receptor accessory protein (IL-1RAcP). IL-1R2 neutralizes IL-1 either as a surface decoy receptor or in a cleaved and secreted form. IL-1R2 is expressed on B cells, on neutrophils and on in vitro expanded human Tregs.

Reactivity

Mouse

Antibody clone number

Praxy-1-1

Storage

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.