FNab04243

antibody from FineTest Biotech

Targeting: IL1R2 CD121b, IL1RB

Western blot

ELISA

Immunocytochemistry

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Validation data

Product number: FNab04243 - Provider product page
Provider: FineTest Biotech
Product name: IL1R2 antibody
Antibody type: Monoclonal
Antigen: Recombinant protein fragment
Description: Non-signaling receptor for IL1A, IL1B and IL1RN. Reduces IL1B activities. Serves as a decoy receptor by competetive binding to IL1B and preventing its binding to IL1R1. Also modulates cellular response through non-signaling association with IL1RAP after binding to IL1B. IL1R2(membrane and secreted forms) preferentially binds IL1B and poorly IL1A and IL1RN. The secreted IL1R2 recruits secreted IL1RAP with high affinity; this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors.
Reactivity: Human, Mouse
Host: Mouse
Conjugate: Unconjugated
Antigen sequence: interleukin 1 receptor, type II
Epitope: IgG1
Isotype: IgG
Antibody clone number: 7G9
Vial size: 100¦Ìg
Concentration: Protein A+G purification
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)

IL1R2 protein structure - FNab04243 shown in red.