Antibody data
- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 15170-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15170-1-AP, RRID:AB_2229978
- Product name
- CRAT antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated CRAT antibody (Cat. #15170-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Artemether regulates liver glycogen and lipid utilization through mitochondrial pyruvate oxidation in db/db mice.
Stable isotope-labeled carnitine reveals its rapid transport into muscle cells and acetylation during contraction.
TGF-β1 attenuates mitochondrial bioenergetics in pulmonary arterial endothelial cells via the disruption of carnitine homeostasis.
Dissociation of Muscle Insulin Resistance from Alterations in Mitochondrial Substrate Preference.
Proximal Tubular Cell-Specific Ablation of Carnitine Acetyltransferase Causes Tubular Disease and Secondary Glomerulosclerosis.
Organelle-Derived Acetyl-CoA Promotes Prostate Cancer Cell Survival, Migration, and Metastasis via Activation of Calmodulin Kinase II.
Carnitine acetyltransferase (CRAT) expression in macrophages is dispensable for nutrient stress sensing and inflammation.
Disruption of endothelial cell mitochondrial bioenergetics in lambs with increased pulmonary blood flow.
Role of carnitine acetyl transferase in regulation of nitric oxide signaling in pulmonary arterial endothelial cells.
Weng W, Shen L, Yu X, Yuan R, Shao M, Han P, Sun H
American journal of translational research 2024;16(1):27-38
American journal of translational research 2024;16(1):27-38
Stable isotope-labeled carnitine reveals its rapid transport into muscle cells and acetylation during contraction.
Furuichi Y, Goto-Inoue N, Uchida S, Masuda S, Manabe Y, Fujii NL
Heliyon 2023 Apr;9(4):e15281
Heliyon 2023 Apr;9(4):e15281
TGF-β1 attenuates mitochondrial bioenergetics in pulmonary arterial endothelial cells via the disruption of carnitine homeostasis.
Sun X, Lu Q, Yegambaram M, Kumar S, Qu N, Srivastava A, Wang T, Fineman JR, Black SM
Redox biology 2020 Sep;36:101593
Redox biology 2020 Sep;36:101593
Dissociation of Muscle Insulin Resistance from Alterations in Mitochondrial Substrate Preference.
Song JD, Alves TC, Befroy DE, Perry RJ, Mason GF, Zhang XM, Munk A, Zhang Y, Zhang D, Cline GW, Rothman DL, Petersen KF, Shulman GI
Cell metabolism 2020 Nov 3;32(5):726-735.e5
Cell metabolism 2020 Nov 3;32(5):726-735.e5
Proximal Tubular Cell-Specific Ablation of Carnitine Acetyltransferase Causes Tubular Disease and Secondary Glomerulosclerosis.
Kruger C, Nguyen TT, Breaux C, Guillory A, Mangelli M, Fridianto KT, Kovalik JP, Burk DH, Noland RC, Mynatt R, Stadler K
Diabetes 2019 Apr;68(4):819-831
Diabetes 2019 Apr;68(4):819-831
Organelle-Derived Acetyl-CoA Promotes Prostate Cancer Cell Survival, Migration, and Metastasis via Activation of Calmodulin Kinase II.
Yu G, Cheng CJ, Lin SC, Lee YC, Frigo DE, Yu-Lee LY, Gallick GE, Titus MA, Nutt LK, Lin SH
Cancer research 2018 May 15;78(10):2490-2502
Cancer research 2018 May 15;78(10):2490-2502
Carnitine acetyltransferase (CRAT) expression in macrophages is dispensable for nutrient stress sensing and inflammation.
Goldberg EL, Dixit VD
Molecular metabolism 2017 Feb;6(2):219-225
Molecular metabolism 2017 Feb;6(2):219-225
Disruption of endothelial cell mitochondrial bioenergetics in lambs with increased pulmonary blood flow.
Sun X, Sharma S, Fratz S, Kumar S, Rafikov R, Aggarwal S, Rafikova O, Lu Q, Burns T, Dasarathy S, Wright J, Schreiber C, Radman M, Fineman JR, Black SM
Antioxidants & redox signaling 2013 May 10;18(14):1739-52
Antioxidants & redox signaling 2013 May 10;18(14):1739-52
Role of carnitine acetyl transferase in regulation of nitric oxide signaling in pulmonary arterial endothelial cells.
Sharma S, Sun X, Agarwal S, Rafikov R, Dasarathy S, Kumar S, Black SM
International journal of molecular sciences 2012 Dec 21;14(1):255-72
International journal of molecular sciences 2012 Dec 21;14(1):255-72
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Supportive validation
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- Proteintech Group (provider)
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- Experimental details
- The CRAT antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human CRAT. This antibody recognizes human,mouse,rat antigen. The CRAT antibody has been validated for the following applications: ELISA, WB analysis.