CRAT

This gene encodes carnitine O-acetyltransferase, a member of the carnitine acyltransferase family and a key metabolic pathway enzyme which plays an important role in energy homeostasis and fat metabolism. This enzyme catalyzes the reversible transfer of acyl groups from an acyl-CoA thioester to carnitine and regulates the ratio of acyl-CoA/CoA. It is found in both the mitochondria and the peroxisome. Alternative splicing results in transcript variants encoding different isoforms that may localize to different subcellular compartments. [provided by RefSeq, Oct 2016]

Description

carnitine O-acetyltransferase

Protein family

Enzymes, Mapped to neXtProt, Mapped to UniProt SWISS-PROT, Predicted intracellular proteins, Protein evidence (Peptideatlas), Transporters

Chromosome

9:q34.11 (129094794 - 129111189)

Ensembl ID

ENSG00000095321  (ver. 99.38)

Orthologs

Mouse Crat: ENSMUSG00000026853

UniProt

P43155

neXtProt

NX_P43155

Human splice variants
Mouse splice variants