BS8160

antibody from Bioworld Technology, Inc
Targeting: CRAT CAT1
Provider product page for BS8160
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS8160 - Provider product page
Provider
Bioworld Technology, Inc
Product name
CRAT polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human CRAT.
Description
Aging affects oxidative metabolism in liver and other tissues. Carnitine acyltransferases are key enzymes of this process in mitochondria. Carnitine acetyltransferase (CAT, CRAT) catalyzes the reversible conversion of acetyl-CoA and carnitine to acetylcarnitine and CoA. The essential functions of CAT are to regenerate CoA, which allows peroxisomal b-oxidation to proceed, and to facilitate transport of acetyl moieties to mitochondria for oxidation. More than 70% of CAT is located in the mitochondrial matrix and it is also located in the endoplasmic reticulum, peroxisomal and mitochondrial inner membrane. An age associated decrease in CAT activity has been reported in many rat systems. The human gene encoding CAT maps to chromosome 9q34.1 and encodes a protein that contains a peroxisomal targeting signal and is expressed mostly in skeletal muscle, and less in heart, liver and pancreas. Total CAT activity is induced by acetate and fatty acids, and repressed by glucose.
Reactivity
Human, Mouse
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
CRAT protein structure - BS8160 shown in red.