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Learn10818-1-AP
antibody from Proteintech Group
Targeting: ERCC2
EM9, MAG, MGC102762, MGC126218, MGC126219, XPD
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [17]
- Comments [0]
- Validations
- Western blot [1]
- Immunoprecipitation [1]
- Immunohistochemistry [1]
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- Product number
- 10818-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10818-1-AP, RRID:AB_2231330
- Product name
- ERCC2 antibody
- Antibody type
- Polyclonal
- Description
- ERCC2 antibody (Cat. #10818-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IHC, IP, WB, ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Arid1a Deficiency Drives Aristolochic Acid-Induced Liver Tumorigenesis through Ctnnb1 Mutation and Defective Nucleotide Excision Repair.
XPD Regulates MIAT/miR-29a-3p/COL4A1 Axis to Impede Hepatocellular Carcinoma Development.
PCP protein Prickle 1 regulates Sertoli cell and testis function via cytoskeletal organization through the recruitment of multiple regulatory proteins.
Impaired Iron-Sulfur Cluster Synthesis Induces Mitochondrial PARthanatos in Diabetic Cardiomyopathy.
FDX2, an iron-sulfur cluster assembly factor, is essential to prevent cellular senescence, apoptosis or ferroptosis of ovarian cancer cells.
CIAO1 loss of function causes a neuromuscular disorder with compromise of nucleocytoplasmic Fe-S enzymes.
The m(6)A reader YTHDC2 regulates UVB-induced DNA damage repair and histone modification.
The ribotoxic stress response drives acute inflammation, cell death, and epidermal thickening in UV-irradiated skin in vivo.
Map-1a regulates Sertoli cell BTB dynamics through the cytoskeletal organization of microtubule and F-actin.
Triptolide enhances carboplatin-induced apoptosis by inhibiting nucleotide excision repair (NER) activity in melanoma.
NAT10 regulates the repair of UVB-induced DNA damage and tumorigenicity.
Proteomic analysis predicts anti-angiogenic resistance in recurred glioblastoma.
Predictive value of ERCC1, ERCC2, ERCC4, and glutathione S-Transferase Pi expression for the efficacy and safety of FOLFIRINOX in patients with unresectable pancreatic cancer.
Aberrant methylation of nucleotide excision repair genes is associated with chronic arsenic poisoning.
MiR-770-5p inhibits cisplatin chemoresistance in human ovarian cancer by targeting ERCC2.
Synchronous detection of miRNAs, their targets and downstream proteins in transferred FFPE sections: applications in clinical and basic research.
Very low prevalence of XPD K751Q polymorphism and its association with XPD expression and outcomes of FOLFOX-4 treatment in Asian patients with colorectal carcinoma.
Wang L, Bai SH, Song SJ, Zhang XL, Shang XY, Lu ZN, Cui XF, Zhu XL, Han ZG
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Jan;13(3):e13981
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Jan;13(3):e13981
XPD Regulates MIAT/miR-29a-3p/COL4A1 Axis to Impede Hepatocellular Carcinoma Development.
Wang Q, Ruan Q, Ding H
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 May 31;39(10):e70611
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 May 31;39(10):e70611
PCP protein Prickle 1 regulates Sertoli cell and testis function via cytoskeletal organization through the recruitment of multiple regulatory proteins.
Wang L, Bu T, Gao S, Yun D, Chen H, Cheng CY, Sun F
American journal of physiology. Cell physiology 2025 Jun 1;328(6):C2032-C2056
American journal of physiology. Cell physiology 2025 Jun 1;328(6):C2032-C2056
Impaired Iron-Sulfur Cluster Synthesis Induces Mitochondrial PARthanatos in Diabetic Cardiomyopathy.
Wang M, Zhang S, Tian J, Yang F, Chen H, Bai S, Kang J, Pang K, Huang J, Dong M, Dong S, Tian Z, Fang S, Fan H, Lu F, Yu B, Li S, Zhang W
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jan;12(1):e2406695
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jan;12(1):e2406695
FDX2, an iron-sulfur cluster assembly factor, is essential to prevent cellular senescence, apoptosis or ferroptosis of ovarian cancer cells.
Miyahara S, Ohuchi M, Nomura M, Hashimoto E, Soga T, Saito R, Hayashi K, Sato T, Saito M, Yamashita Y, Shimada M, Yaegashi N, Yamada H, Tanuma N
The Journal of biological chemistry 2024 Sep;300(9):107678
The Journal of biological chemistry 2024 Sep;300(9):107678
CIAO1 loss of function causes a neuromuscular disorder with compromise of nucleocytoplasmic Fe-S enzymes.
Maio N, Orbach R, Zaharieva IT, Töpf A, Donkervoort S, Munot P, Mueller J, Willis T, Verma S, Peric S, Krishnakumar D, Sudhakar S, Foley AR, Silverstein S, Douglas G, Pais L, DiTroia S, Grunseich C, Hu Y, Sewry C, Sarkozy A, Straub V, Muntoni F, Rouault TA, Bönnemann CG
The Journal of clinical investigation 2024 Jun 17;134(12)
The Journal of clinical investigation 2024 Jun 17;134(12)
The m(6)A reader YTHDC2 regulates UVB-induced DNA damage repair and histone modification.
Yang Z, Verghese M, Yang S, Shah P, He YY
Photochemistry and photobiology 2024 Jul-Aug;100(4):1031-1040
Photochemistry and photobiology 2024 Jul-Aug;100(4):1031-1040
The ribotoxic stress response drives acute inflammation, cell death, and epidermal thickening in UV-irradiated skin in vivo.
Vind AC, Wu Z, Firdaus MJ, Snieckute G, Toh GA, Jessen M, Martínez JF, Haahr P, Andersen TL, Blasius M, Koh LF, Maartensson NL, Common JEA, Gyrd-Hansen M, Zhong FL, Bekker-Jensen S
Molecular cell 2024 Dec 19;84(24):4774-4789.e9
Molecular cell 2024 Dec 19;84(24):4774-4789.e9
Map-1a regulates Sertoli cell BTB dynamics through the cytoskeletal organization of microtubule and F-actin.
Wang L, Yan M, Bu T, Wu X, Li L, Silvestrini B, Sun F, Cheng CY, Chen H
Reproductive biology and endocrinology : RB&E 2024 Apr 3;22(1):36
Reproductive biology and endocrinology : RB&E 2024 Apr 3;22(1):36
Triptolide enhances carboplatin-induced apoptosis by inhibiting nucleotide excision repair (NER) activity in melanoma.
Wang G, Guo H, Ren Y, Chen W, Wang Y, Li J, Liu H, Xing J, Zhang Y, Li N
Frontiers in pharmacology 2023;14:1157433
Frontiers in pharmacology 2023;14:1157433
NAT10 regulates the repair of UVB-induced DNA damage and tumorigenicity.
Yang Z, Wilkinson E, Cui YH, Li H, He YY
Toxicology and applied pharmacology 2023 Oct 15;477:116688
Toxicology and applied pharmacology 2023 Oct 15;477:116688
Proteomic analysis predicts anti-angiogenic resistance in recurred glioblastoma.
Jeon H, Byun J, Kang H, Kim K, Lee E, Kim JH, Hong CK, Song SW, Kim YH, Chong S, Kim JH, Nam SJ, Park JE, Lee S
Journal of translational medicine 2023 Feb 2;21(1):69
Journal of translational medicine 2023 Feb 2;21(1):69
Predictive value of ERCC1, ERCC2, ERCC4, and glutathione S-Transferase Pi expression for the efficacy and safety of FOLFIRINOX in patients with unresectable pancreatic cancer.
Tezuka S, Ueno M, Kobayashi S, Morimoto M, Ohkawa S, Hirotani A, Tozuka Y, Moriya S, Nakamura Y, Miyagi Y, Sugimori M, Maeda S
American journal of cancer research 2018;8(10):2096-2105
American journal of cancer research 2018;8(10):2096-2105
Aberrant methylation of nucleotide excision repair genes is associated with chronic arsenic poisoning.
Zhang A, Li H, Xiao Y, Chen L, Zhu X, Li J, Ma L, Pan X, Chen W, He Z
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 2017 Jul;22(5):429-438
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 2017 Jul;22(5):429-438
MiR-770-5p inhibits cisplatin chemoresistance in human ovarian cancer by targeting ERCC2.
Zhao H, Yu X, Ding Y, Zhao J, Wang G, Wu X, Jiang J, Peng C, Guo GZ, Cui S
Oncotarget 2016 Aug 16;7(33):53254-53268
Oncotarget 2016 Aug 16;7(33):53254-53268
Synchronous detection of miRNAs, their targets and downstream proteins in transferred FFPE sections: applications in clinical and basic research.
Zhao JY, Liu CQ, Zhao HN, Ding YF, Bi T, Wang B, Lin XC, Guo G, Cui SY
Methods (San Diego, Calif.) 2012 Oct;58(2):156-63
Methods (San Diego, Calif.) 2012 Oct;58(2):156-63
Very low prevalence of XPD K751Q polymorphism and its association with XPD expression and outcomes of FOLFOX-4 treatment in Asian patients with colorectal carcinoma.
Lai JI, Tzeng CH, Chen PM, Lin JK, Lin TC, Chen WS, Jiang JK, Wang HS, Wang WS
Cancer science 2009 Jul;100(7):1261-6
Cancer science 2009 Jul;100(7):1261-6
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 10818-1-AP(ERCC2 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-ERCC2 (IP:10818-1-AP, 5ug; Detection:10818-1-AP 1:500) with K-562 cells lysate 8000ug.
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The ERCC2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human ERCC2. This antibody recognizes human antigen. The ERCC2 antibody has been validated for the following applications: ELISA, WB, IHC, IP analysis.
