FNab02833

antibody from FineTest Biotech

Targeting: ERCC2 EM9, MAG, MGC102762, MGC126218, MGC126219, XPD

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ELISA

Immunoprecipitation

Immunohistochemistry

Antibody data

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Validation data

Product number: FNab02833 - Provider product page
Provider: FineTest Biotech
Product name: ERCC2 antibody
Antibody type: Polyclonal
Antigen: Recombinant protein fragment
Description: ATP-dependent 5'-3' DNA helicase, component of the core-TFIIH basal transcription factor. Involved in nucleotide excision repair(NER) of DNA by opening DNA around the damage, and in RNA transcription by RNA polymerase II by anchoring the CDK-activating kinase(CAK) complex, composed of CDK7, cyclin H and MAT1, to the core-TFIIH complex. Involved in the regulation of vitamin-D receptor activity. As part of the mitotic spindle-associated MMXD complex it plays a role in chromosome segregation. Might have a role in aging process and could play a causative role in the generation of skin cancers.
Reactivity: Human
Host: Rabbit
Conjugate: Unconjugated
Antigen sequence: excision repair cross-complementing rodent repair deficiency, compleme ntation group 2
Epitope: IgG
Isotype: IgG
Vial size: 100¦Ìg
Concentration: Immunogen affinity purified
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)

ERCC2 protein structure - FNab02833 shown in red.