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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [5]
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- Product number
- ABIN357783 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Palmitoyl-Protein Thioesterase 1 (PPT1) (N-Term) antibody
- Antibody type
- Polyclonal
- Description
- Protein G Chromatography eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Epitope
- N-Term
- Vial size
- 0.4 mL
- Storage
- Store the antibody undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references The crystal structure of palmitoyl protein thioesterase-2 (PPT2) reveals the basis for divergent substrate specificities of the two lysosomal thioesterases, PPT1 and PPT2.
The neuronal ceroid lipofuscinoses: mutations in different proteins result in similar disease.
Neuronal ceroid lipofuscinoses caused by defects in soluble lysosomal enzymes (CLN1 and CLN2).
Lipid thioesters derived from acylated proteins accumulate in infantile neuronal ceroid lipofuscinosis: correction of the defect in lymphoblasts by recombinant palmitoyl-protein thioesterase.
Didemnin binds to the protein palmitoyl thioesterase responsible for infantile neuronal ceroid lipofuscinosis.
Calero G, Gupta P, Nonato MC, Tandel S, Biehl ER, Hofmann SL, Clardy J
The Journal of biological chemistry 2003 Sep 26;278(39):37957-64
The Journal of biological chemistry 2003 Sep 26;278(39):37957-64
The neuronal ceroid lipofuscinoses: mutations in different proteins result in similar disease.
Weimer JM, Kriscenski-Perry E, Elshatory Y, Pearce DA
Neuromolecular medicine 2002;1(2):111-24
Neuromolecular medicine 2002;1(2):111-24
Neuronal ceroid lipofuscinoses caused by defects in soluble lysosomal enzymes (CLN1 and CLN2).
Hofmann SL, Atashband A, Cho SK, Das AK, Gupta P, Lu JY
Current molecular medicine 2002 Aug;2(5):423-37
Current molecular medicine 2002 Aug;2(5):423-37
Lipid thioesters derived from acylated proteins accumulate in infantile neuronal ceroid lipofuscinosis: correction of the defect in lymphoblasts by recombinant palmitoyl-protein thioesterase.
Lu JY, Verkruyse LA, Hofmann SL
Proceedings of the National Academy of Sciences of the United States of America 1996 Sep 17;93(19):10046-50
Proceedings of the National Academy of Sciences of the United States of America 1996 Sep 17;93(19):10046-50
Didemnin binds to the protein palmitoyl thioesterase responsible for infantile neuronal ceroid lipofuscinosis.
Crews CM, Lane WS, Schreiber SL
Proceedings of the National Academy of Sciences of the United States of America 1996 Apr 30;93(9):4316-9
Proceedings of the National Academy of Sciences of the United States of America 1996 Apr 30;93(9):4316-9
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