Tissue expression
Cell line expression
Protein structure
PPT1
Palmitoyl-protein thioesterase 1CLN1, INCL, PPT
The protein encoded by this gene is a small glycoprotein involved in the catabolism of lipid-modified proteins during lysosomal degradation. The encoded enzyme removes thioester-linked fatty acyl groups such as palmitate from cysteine residues. Defects in this gene are a cause of infantile neuronal ceroid lipofuscinosis 1 (CLN1, or INCL) and neuronal ceroid lipofuscinosis 4 (CLN4). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]
Top validated antibodies |
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| LSBio | Monoclonal |
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| GeneTex | 1 references | Polyclonal |
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| Novus Biologicals | 1 references | Polyclonal |
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| Boster Biological Technology | 1 references | Monoclonal |
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| Abnova Corporation | 3 references | Polyclonal |
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