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- References [10]
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- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 18236-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#18236-1-AP, RRID:AB_10859822
- Product name
- TRPC6 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated TRPC6 antibody (Cat. #18236-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: FC, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references The calcium channel TRPC6 promotes chemotherapy-induced persistence by regulating integrin α6 mRNA splicing.
Deciphering the pharmacological mechanisms of Rostellularia procumbens (L) Nees. Extract alleviates adriamycin-induced nephropathy in vivo and in vitro.
Dexmedetomidine Alleviates Neuropathic Pain via the TRPC6-p38 MAPK Pathway in the Dorsal Root Ganglia of Rats.
Sildenafil protects against pulmonary hypertension induced by hypoxia in neonatal rats via activation of PPARγ‑mediated downregulation of TRPC.
TRPC6 interacted with K(Ca)1.1 channels to regulate the proliferation and apoptosis of glioma cells.
Amelioration of circadian disruption and calcium-handling protein defects by choline alleviates cardiac remodeling in abdominal aorta coarctation rats.
Regenerative Metaplastic Clones in COPD Lung Drive Inflammation and Fibrosis.
Nongenetic optical modulation of neural stem cell proliferation and neuronal/glial differentiation.
Catalpol alleviates adriamycin-induced nephropathy by activating the SIRT1 signalling pathway in vivo and in vitro.
TRPC6 channel translocation into phagosomal membrane augments phagosomal function.
Mukhopadhyay D, Goel HL, Xiong C, Goel S, Kumar A, Li R, Zhu LJ, Clark JL, Brehm MA, Mercurio AM
Cell reports 2023 Nov 28;42(11):113347
Cell reports 2023 Nov 28;42(11):113347
Deciphering the pharmacological mechanisms of Rostellularia procumbens (L) Nees. Extract alleviates adriamycin-induced nephropathy in vivo and in vitro.
Ai Z, Wang M, Zhou Y, Yuan D, Jian Q, Wu S, Liu B, Yang Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 May;113:154736
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 May;113:154736
Dexmedetomidine Alleviates Neuropathic Pain via the TRPC6-p38 MAPK Pathway in the Dorsal Root Ganglia of Rats.
Xu S, Yi Y, Wang Y, Wang P, Zhao Y, Feng W
Journal of pain research 2022;15:2437-2448
Journal of pain research 2022;15:2437-2448
Sildenafil protects against pulmonary hypertension induced by hypoxia in neonatal rats via activation of PPARγ‑mediated downregulation of TRPC.
Huang W, Liu N, Tong X, Du Y
International journal of molecular medicine 2022 Feb;49(2)
International journal of molecular medicine 2022 Feb;49(2)
TRPC6 interacted with K(Ca)1.1 channels to regulate the proliferation and apoptosis of glioma cells.
Yin H, Cheng H, Li P, Yang Z
Archives of biochemistry and biophysics 2022 Aug 15;725:109268
Archives of biochemistry and biophysics 2022 Aug 15;725:109268
Amelioration of circadian disruption and calcium-handling protein defects by choline alleviates cardiac remodeling in abdominal aorta coarctation rats.
He X, Yang S, Deng J, Wu Q, Zang WJ
Laboratory investigation; a journal of technical methods and pathology 2021 Jul;101(7):878-896
Laboratory investigation; a journal of technical methods and pathology 2021 Jul;101(7):878-896
Regenerative Metaplastic Clones in COPD Lung Drive Inflammation and Fibrosis.
Rao W, Wang S, Duleba M, Niroula S, Goller K, Xie J, Mahalingam R, Neupane R, Liew AA, Vincent M, Okuda K, O'Neal WK, Boucher RC, Dickey BF, Wechsler ME, Ibrahim O, Engelhardt JF, Mertens TCJ, Wang W, Jyothula SSK, Crum CP, Karmouty-Quintana H, Parekh KR, Metersky ML, McKeon FD, Xian W
Cell 2020 May 14;181(4):848-864.e18
Cell 2020 May 14;181(4):848-864.e18
Nongenetic optical modulation of neural stem cell proliferation and neuronal/glial differentiation.
Wang M, Xu Z, Liu Q, Sun W, Jiang B, Yang K, Li J, Gong Y, Liu Q, Liu D, Li X
Biomaterials 2019 Dec;225:119539
Biomaterials 2019 Dec;225:119539
Catalpol alleviates adriamycin-induced nephropathy by activating the SIRT1 signalling pathway in vivo and in vitro.
Zhang J, Bi R, Meng Q, Wang C, Huo X, Liu Z, Wang C, Sun P, Sun H, Ma X, Wu J, Liu K
British journal of pharmacology 2019 Dec;176(23):4558-4573
British journal of pharmacology 2019 Dec;176(23):4558-4573
TRPC6 channel translocation into phagosomal membrane augments phagosomal function.
Riazanski V, Gabdoulkhakova AG, Boynton LS, Eguchi RR, Deriy LV, Hogarth DK, Loaëc N, Oumata N, Galons H, Brown ME, Shevchenko P, Gallan AJ, Yoo SG, Naren AP, Villereal ML, Beacham DW, Bindokas VP, Birnbaumer L, Meijer L, Nelson DJ
Proceedings of the National Academy of Sciences of the United States of America 2015 Nov 24;112(47):E6486-95
Proceedings of the National Academy of Sciences of the United States of America 2015 Nov 24;112(47):E6486-95
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse lung tissue were subjected to SDS PAGE followed by western blot with 18236-1-AP(TRPC6 antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The TRPC6 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human TRPC6. This antibody recognizes human, mouse antigen. The TRPC6 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
