Tissue expression
Cell line expression
Protein structure
TRPC6
Transient receptor potential cation channel subfamily C member 6FSGS2, TRP6
The protein encoded by this gene forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2). [provided by RefSeq, Mar 2009]
Top validated antibodies |
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| Proteintech Group | 10 references | Polyclonal |
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| LSBio | Polyclonal |
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| Invitrogen Antibodies | Polyclonal |
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| GeneTex | Polyclonal |
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| Novus Biologicals | 4 references | Polyclonal |
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