Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- NBP1-00142 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NBP1-00142, RRID:AB_1504382
- Product name
- Goat Polyclonal TRPC6 Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified.
- Reactivity
- Human, Mouse
- Host
- Goat
- Isotype
- IgG
- Vial size
- 0.1 mg
- Concentration
- 0.5 mg/ml
- Storage
- Store at -20C. Avoid freeze-thaw cycles.
Submitted references Differences in TRPC3 and TRPC6 channels assembly in mesenteric vascular smooth muscle cells in essential hypertension.
NOX2 interacts with podocyte TRPC6 channels and contributes to their activation by diacylglycerol: essential role of podocin in formation of this complex.
Opposing effects of podocin on the gating of podocyte TRPC6 channels evoked by membrane stretch or diacylglycerol.
TRPC6 contributes to the Ca(2+) leak of human erythrocytes.
Álvarez-Miguel I, Cidad P, Pérez-García MT, López-López JR
The Journal of physiology 2017 Mar 1;595(5):1497-1513
The Journal of physiology 2017 Mar 1;595(5):1497-1513
NOX2 interacts with podocyte TRPC6 channels and contributes to their activation by diacylglycerol: essential role of podocin in formation of this complex.
Kim EY, Anderson M, Wilson C, Hagmann H, Benzing T, Dryer SE
American journal of physiology. Cell physiology 2013 Nov 1;305(9):C960-71
American journal of physiology. Cell physiology 2013 Nov 1;305(9):C960-71
Opposing effects of podocin on the gating of podocyte TRPC6 channels evoked by membrane stretch or diacylglycerol.
Anderson M, Kim EY, Hagmann H, Benzing T, Dryer SE
American journal of physiology. Cell physiology 2013 Aug 1;305(3):C276-89
American journal of physiology. Cell physiology 2013 Aug 1;305(3):C276-89
TRPC6 contributes to the Ca(2+) leak of human erythrocytes.
Foller M, Kasinathan RS, Koka S, Lang C, Shumilina E, Birnbaumer L, Lang F, Huber SM
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2008;21(1-3):183-92
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2008;21(1-3):183-92
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Supportive validation
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- Novus Biologicals (provider)
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- Experimental details
- Western Blot: TRPC6 Antibody [NBP1-00142] - Analysis of TRPC6 in human placenta lysate (35ug protein in RIPA buffer) using this antibody at 0.03 ug/ml. Primary incubation was 1 hour. Detected by chemiluminescence.