Tissue expression
Cell line expression
Protein structure
RNASE1
Ribonuclease A family member 1, pancreaticRAC1, RNS1
This gene encodes a member of the pancreatic-type of secretory ribonucleases, a subset of the ribonuclease A superfamily. The encoded endonuclease cleaves internal phosphodiester RNA bonds on the 3'-side of pyrimidine bases. It prefers poly(C) as a substrate and hydrolyzes 2',3'-cyclic nucleotides, with a pH optimum near 8.0. The encoded protein is monomeric and more commonly acts to degrade ds-RNA over ss-RNA. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Atlas Antibodies | 4 references | Polyclonal |
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| GeneTex | 1 references | Polyclonal |
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| LSBio | Polyclonal |
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| Novus Biologicals | 1 references | Polyclonal |
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| antibodies-online | Polyclonal |
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