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- Antibody Data
- Antigen structure
- References [4]
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- Immunohistochemistry [1]
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- Product number
- HPA001140 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA001140, RRID:AB_1079816
- Product name
- Anti-RNASE1
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human RNASE1, Gene description: ribonuclease, RNase A family, 1 (pancreatic), Alternative Gene Names: RNS1, Validated applications: ICC, IHC, WB, Uniprot ID: P07998, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.1 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references Targeting ALK averts ribonuclease 1-induced immunosuppression and enhances antitumor immunity in hepatocellular carcinoma.
Ribonuclease 1 Enhances Antitumor Immunity against Breast Cancer by Boosting T cell Activation
Human ribonuclease 1 serves as a secretory ligand of ephrin A4 receptor and induces breast tumor initiation
The expression and localization of RNase and RNase inhibitor in blood cells and vascular endothelial cells in homeostasis of the vascular system
Liu C, Zhou C, Xia W, Zhou Y, Qiu Y, Weng J, Zhou Q, Chen W, Wang YN, Lee HH, Wang SC, Kuang M, Yu D, Ren N, Hung MC
Nature communications 2024 Feb 2;15(1):1009
Nature communications 2024 Feb 2;15(1):1009
Ribonuclease 1 Enhances Antitumor Immunity against Breast Cancer by Boosting T cell Activation
Wang Y, Lee H, Jiang Z, Chan L, Hortobagyi G, Yu D, Hung M
International Journal of Biological Sciences 2023;19(10):2957-2973
International Journal of Biological Sciences 2023;19(10):2957-2973
Human ribonuclease 1 serves as a secretory ligand of ephrin A4 receptor and induces breast tumor initiation
Lee H, Wang Y, Yang W, Xia W, Wei Y, Chan L, Wang Y, Jiang Z, Xu S, Yao J, Qiu Y, Hsu Y, Hwang W, Yan M, Cha J, Hsu J, Shen J, Ye Y, Wu X, Hou M, Tseng L, Wang S, Pan M, Yang C, Wang Y, Yamaguchi H, Pang D, Hortobagyi G, Yu D, Hung M
Nature Communications 2021;12(1)
Nature Communications 2021;12(1)
The expression and localization of RNase and RNase inhibitor in blood cells and vascular endothelial cells in homeostasis of the vascular system
Schulz C, Ohashi A, Murata A, Cho Y, Ichinose S, Sakamaki Y, Nishio M, Hoshi O, Fischer S, Preissner K, Koyama T
PLOS ONE 2017;12(3):e0174237
PLOS ONE 2017;12(3):e0174237
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Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Orthogonal validation
- Main image
- Experimental details
- Immunohistochemistry analysis in human pancreas and prostate tissues using HPA001140 antibody. Corresponding RNASE1 RNA-seq data are presented for the same tissues.
- Sample type
- Human
- Protocol
- Protocol
